郭兆娟++袁一平++孔李婷++贾晓玉++王宁宁++戴莹++翟华强

[摘要]升降浮沉药性理论是指导临床组方遣药的重要依据之一。通过古籍及文献研究得知，升降浮沉理论萌芽于《黄帝内经》，实践于《伤寒杂病论》，成立于《医学启源》，发展于《本草纲目》及现代。升降浮沉理论目前大多停留在理论研究阶段，实验研究少有，临床研究中其对组方的指导主要包括升降相反、升降相生、以升为主和以降为主4种形式。运用升降浮沉药性配伍的药对主要有升药配对、升降配對和降药配对3种。利用现代生物学技术开展升降浮沉药性实验研究，揭示升降浮沉的科学内涵，将有助于其更科学的指导临床用药。

[关键词]升降浮沉；中药药性；历史源流；药对配伍

Origin of lifting and lowering theory and its herb pair study

GUO Zhaojuan， YUAN Yiping， KONG Liting， JIA Xiaoyu， WANG Ningning， DAI Ying， ZHAI Huaqiang*

（College of Traditional Chinese Medicine， Beijing University of Chinese Medicine， Beijing 100102， China）

[Abstract]Lifting and lowering theory is one of the important basis for guiding clinical medication Through the study of ancient books and literature， we learned that lifting and lowering theory was originated in Huangdi Neijing， practiced more in the Shanghan Zabing Lun， established in Yixue Qiyuan， and developed in Compendium of Materia Medica and now However， lifting and lowering theory is now mostly stagnated in the theoretical stage， with few experimental research In the clinical study， the guiding role of lifting and lowering theory to prescriptions？mainly includes opposite？role？of lift and lower medicine property， mutual promotion of lift and lower medicine property， main role of lift medicine property and main role of lower medicine property Under the guidance of lifting and lowering theory， the herb pair compatibility include herb combination of lift medicine property， herb combination of lift and lower medicine property and herb combination of lower medicine property Modern biological technology was used in this study to carry out experimental research on the lifting and lowering theory， revealing the scientific connotation of it， which will help to promote clinical rational drug use.

[Key words]lifting and lowering theory； Chinese herbal property； historical origin； herb pair

升降浮沉是中药药性理论的重要组成部分，也是指导临床用药的重要原则之一。升降浮沉的含义有二：一是药物针对病势的作用趋向，升即上升，降即下降，浮即向外，沉即向内；二是药物对脏腑经络生理趋向的调节。它是从药物的作用趋势上对中药功效的形象概括。中药升降浮沉药性理论作为支撑中医药学尤其是中药临床应用的重要支柱之一，长期以来不断发展完善，这种不断完善同时也是不断被验证与证实的过程。本文旨在研究升降浮沉理论起源及其对临床组方遣药的指导作用，分析升降浮沉理论当前的研究及应用现状，冀以为升降浮沉理论的发展及中医临床科学合理用药提供有益借鉴。……