黎友隆

[摘要] 目的 探讨健脾通络汤治疗脾胃虚弱型慢性萎缩性胃炎的临床疗效。 方法 根据随机数字表法，将2015年1月～2016年10月我院80例脾胃虚弱型慢性萎缩性胃炎患者分成对照组（西药治疗）和观察组（健脾通络汤），每组各40例，比较两组治疗的临床疗效、中医症候积分改善情况，以及不良反应。 结果 与对照组相比，观察组治疗的总有效率明显增高，差异有统计学意义（P<0.05）；与对照组相比，观察组中医症候积分显著下降，差异有统计学意义（P<0.05）；治疗期间两组都没有出现明显的不良反应。 结论 健脾通络汤治疗脾胃虚弱型慢性萎缩性胃炎的疗效显著，明显改善中医证候，具有较高治疗安全性，值得临床推广。

[关键词] 健脾通络汤；脾胃虚弱；慢性萎缩性胃炎；中医证候；安全性

[中图分类号] R259 [文献标识码] A [文章编号] 2095-0616（2017）11-56-03

Efficacy research of Jianpi Tongluo decoction in chronic atrophic gastritis

LI Youlong

Department of Traditional Chinese Medicine， Haifeng District People's Hospital， Shanwei 516400， China

[Abstract] Objective To study clinical efficacy of Jianpi Tongluo decoction in chronic atrophic gastritis. Methods 80 patients with chronic atrophic gastritis in our hospital from January 2015 to October 2016 were randomly divided into control group （western drug） and observation group （Jianpi Tongluo decoction） according to the random number method， 40 patients per group. The clinical efficacy of treatment， the improvement of TCM symptoms and signs， and adverse reactions in two groups were compared. Results Compared with control group， the total effective rate of treatment in the observation group was significantly increased， and there was statistical difference （P<0.05）. Compared with the control group， the scores of TCM symptoms and signs in observation group were obviously decreased， and there was statistical difference （P<0.05）. There were no obvious adverse reactions in two groups during treatment period. Conclusion The treatment of Jianpi Tongluo decoction for chronic atrophic gastritis has significant efficacy. It can significantly improve the TCM symptoms. It has higher treatment safety， and it is worthy of clinical promotion.

[Key words] Jianpi Tongluo decoction； Weakness of spleen and stomach； Chronic atrophic gastritis； TCM syndrome； Safety

慢性萎縮性胃炎是以多种胃肠病变特征为主的慢性消化系统疾病，临床症状没有特异性，多数患者发病后很难及时诊断、及时治疗，尤其是伴随异性增生及肠上皮化生的慢性萎缩性胃炎，是一种癌前病变[1-3]。目前，慢性萎缩性胃炎的病因及发病机制，还不是很清楚，还缺乏有效的治疗方法[4-5]。脾胃虚弱型作为慢性萎缩性胃炎中医辨证分型的常见证型。本研究探讨健脾通络汤治疗脾胃虚弱型慢性萎缩性胃炎的临床效果，现将结果报道如下。

1 资料与方法

1.1 一般资料

根据随机数字表法，将2015年1月～2016年10月我院80例脾胃虚弱型慢性萎缩性胃炎患者分成对照组（西药治疗）和观察组（健脾通络汤），每组各40例。所有患者均符合《慢性萎缩性胃炎中医诊疗共识意见》中的相关辨证分型标准（胃镜显示黏膜变薄、苍白、血管清晰可见），入院前一周没有接受药物治疗，排除病理组织学检查显示高度恶性、合并严重重要器官功能障碍、胃部手术史、妊娠期或哺乳期妇女。……