MAC技术下瑞芬太尼麻醉在无痛结肠镜检查中的应用
2017-07-01金学勇祁燕梁桂玲李玉石王国毅
金学勇+祁燕+梁桂玲+李玉石+王国毅



[摘要] 目的 MAC技术下单纯药物(瑞芬太尼)麻醉在无痛结肠镜检查中的有效性及安全性。 方法 方便选取2016年1—12月住院的肠镜预约汉族患者80例列为观察对象,并以随机分配原则分为两组(40例/组),其中给予丙泊芬麻醉为对照组,在MAC技术下应用瑞芬太尼麻醉为观察组,记录两组患者生命体征监测情况,统计其麻醉效果、药物不良反应及麻醉满意度。结果 术中观察组患者心率、血压等生命体征指标相较于对照组更为平稳(P<0.05);且观察组镇静Ramsay等级为(2.0±0.5)级明显优于对照组(3.5±0.8)(P<0.05),同时在两组不良反应发生率比较中观察组为7.50%明显低于对照组的75.00%,差异有统计学意义(P<0.05)。结论 MAC技术下单纯药物(瑞芬太尼)麻醉应用于无痛结肠镜检查麻醉效果可靠,且不良反应更少而用药安全性更高,值得推广应用。
[关键词] MAC技术;丙泊芬;瑞芬太尼;结肠镜麻醉
[中图分类号] R614.24 [文献标识码] A [文章编号] 1674-0742(2017)05(a)-0118-03
[Abstract] Objective To study the efficacy and safety of simple drugs (remifentanil) anesthesia in the diagnosis and treatment of colonoscopy. Methods 80 cases of colonoscopy were divided into two groups (40 cases / group) according to the principle of random distribution. The patients were given propofol Anesthesia was used as the control group. The patients were treated with remifentanil anesthesia as the observation group. The vital signs were recorded and the anesthesia effect, adverse drug reaction and anesthesia satisfaction were recorded. Results The vital signs and blood pressure and other vital signs were more stable (P <0.05). The level of sedation Ramsay was (2.0±0.5) in the observation group was significantly better than that in the control group (3.5±0.8)(P <0.05). At the same time, the observation group was 7.50% lower than the control group (75.00%) ,The difference was statistically significant(P <0.05). Conclusion MAC technique alone (remifentanil) anesthesia in painless colonoscopy anesthetic effect is reliable, and fewer adverse reactions and drug safety is higher, worthy of promotion and application.
[Key words] MAC technology; Propofol; Remifentanil; Colon anesthesia
随着社会的发展,人们对于治疗疾病的需求同时也推动了麻醉技术的不断发展[1]。丙泊芬是临床中常用麻醉药;然据相关文献报道认为[2-3],虽然丙泊芬临床麻醉效果较好,但易发生相关并发症,如注射痛、血压升高等。瑞芬太尼为芬太尼类μ型阿片受体激动剂,其经静脉麻醉时具有操作简单、起效快等特点,且消除半衰期和持续输注半衰期短,同时还具有良好的镇静、镇痛效果,适用于门诊短小手术的麻醉[4]。该研究于2016年1—12月通过对该院80例住院的肠镜预约汉族患者展开不同麻醉方法,进而探讨MAC技术下单一药物(瑞芬太尼)麻醉在结肠镜检查中的有效性及安全性,现报道如下。
1 资料与方法
1.1 一般资料
方便选取于该院住院的肠镜预约汉族患者80例列为观察对象,所有患者均为自愿参与该研究并签订知情同意书。以随机分配原则分为两组(40例/组),其中对照组患者男性25例,女性15例;……
