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子宫动脉栓塞术对有生育要求的子宫疤痕妊娠患者的治疗价值

2017-06-27吴夏筠黄宏伟

中国实用医药 2017年14期

吴夏筠+黄宏伟

【摘要】 目的 探讨子宫动脉栓塞术(UAE)对有生育要求的子宫疤痕妊娠患者的治疗价值。方法 40例子宫疤痕妊娠患者, 根据自愿原则随机分为治疗组与对照组, 每组20例。治疗组行UAE+宫腔镜电切术, 对照组行宫腔镜检查+B超引导下清宫术。对比两组的治疗效果。结果 两组手术均取得成功, 治疗组术中出血量为(6.50±2.35)ml, 少于对照组的(20.00±11.24)ml;术后阴道流血时间、住院时间及血人绒毛膜促性腺激素(HCG)转阴时间分别为(2.10±0.72)、(5.90±0.72)、(12.40±1.93)d, 均短于对照组的(9.20±2.29)、(11.25±1.86)、(37.85±6.78)d, 差异均具有统计学意义(P<0.05)。治疗组术后月经量减少发生率50.0%和宫腔粘连发生率30.0%均高于对照组的15.0%、5.0%, 差异均具有统计学意义(P<0.05)。结论 UAE在子宫疤痕妊娠的治疗中能显著降低大出血的风险, 是安全有效的治疗方法。但术后宫腔粘连发生率极高, 影响患者生育功能, 对仍有生育要求的患者, 应慎重选用。

【关键词】 子宫动脉栓塞术;子宫疤痕妊娠;宫腔粘连

DOI:10.14163/j.cnki.11-5547/r.2017.14.019

【Abstract】 Objective To explore the value of uterine artery embolization (UAE) in the treatment of uterine scar pregnancy patients with fertility requirements. Methods A total of 40 uterine scar pregnancy patients were divided by voluntary principal into treatment group and control group, with 20 cases in each group. The treatment group received UAE + uteroscope electrotomy, and the control group received hysteroscopy examination + ultrasound guided curettage. Therapeutic effect was compared in two groups. Results Both groups had successful operation, and the treatment group had less intraoperative bleeding volume as (6.50±2.35) ml than (20.00±11.24) ml in the control group, and shorter postoperative vaginal bleeding time, hospital stay time and human chorionic gonadotropin (HCG) negative conversion time as (2.10±0.72), (5.90±0.72) and (12.40±1.93) d than (9.20±2.29), (11.25±1.86) and (37.85±6.78) d in the control group. Their difference had statistical significance (P<0.05). The treatment group had higher incidence of postoperative reduced menstrual quantity as 50.0% and incidence of intrauterine adhesion as 30.0% than 15.0% and 5.0% in the control group, and their difference had statistical significance (P<0.05). Conclusion UAE can significantly reduce risks of massive haemorrhage in treating uterine scar pregnancy, and it is a safe and effective treatment method. But it has high incidence of postoperative intrauterine adhesion that can affect reproductive function of patients. So patients with fertility requirements should chosen it carefully.

【Key words】 Uterine artery embolization; Uterine scar pregnancy; Intrauterine adhesion

2010年世界衛生组织公布我国的剖宫产率为46%, 居世界第一。随着剖宫产的增多, 子宫疤痕妊娠的发生率近年来显著升高。UAE具有微创、操作简便、止血迅速有效等优点, 逐渐应用于临床。因子宫疤痕妊娠容易出现大出血等风险, 临床上也越来越多的应用UAE来治疗子宫疤痕妊娠。本研究将本院2008年1月~2015年8月40例因子宫疤痕妊娠在本院住院治疗的患者分为两组, 治疗组20例行UAE+宫腔镜电切术, 对照组20例行宫腔镜检查+B超引导下清宫术, 探讨UAE对有生育要求的子宫疤痕妊娠患者的治疗价值, 现报告如下。

1 资料与方法

1. 1 一般资料 本研究纳入的对象为2008年1月~2015年8月因子宫疤痕妊娠在本院住院治疗的患者40例, 年龄18~35岁, 根据自愿原则将其随机分为治疗组与对照组, 每组20例。两组患者均无明显手术禁忌证。

1. 2 研究方法 治疗组行UAE+宫腔镜电切术:经阴道B超确诊为子宫疤痕妊娠后, 送介入室用直径约1 mm的无菌明胶海绵颗粒栓塞双侧子宫动脉, 经造影证实后拔管。……

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