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老年心脑血管疾病患者疗养康复前后脂代谢比较

2017-05-27刘新华张嘉

中国实用医药 2016年35期

刘新华 张嘉

【摘要】 目的 比較老年心脑血管疾病患者在接受疗养康复前后血脂水平变化, 为临床应用提供理论指导。方法 100例接受康复疗养的老年心血管疾病患者, 所有患者入院后进行有针对性的护理干预。采取自身对照的方法, 比较疗养前后患者的总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、脂蛋白(a)、游离脂肪酸含量, 利用统计学软件进行对比分析。结果 疗养前, 总胆固醇为(6.04±0.35)mmol/L、甘油三脂为(2.38±0.56)mmol/L、高密度脂蛋白胆固醇为(0.86±0.34)mmol/L、低密度脂蛋白胆固醇为(3.10±0.27)mmol/L、脂蛋白(a)为(409.12±56.11)mg/L、游离脂肪酸为(1.45±0.25)mmol/L;

疗养后患者血脂指标分别为(5.35±0.23)mmol/L、(1.62±0.25)mmol/L、(1.20±0.31)mmol/L、(2.89± 0.11)mmol/L、(301.31±24.85)mg/L、(0.75±0.29)mmol/L, 患者疗养后较疗养前的总胆固醇、甘油三酯、低密度脂蛋白胆固醇、脂蛋白(a)、游离脂肪酸含量均有显著下降, 高密度脂蛋白胆固醇含量明显上升(P<0.05)。结论 疗养康复可以改善老年心脑血管疾病患者的血脂代谢水平, 可在临床应用推广。

【关键词】 心脑血管疾病;康复疗养;脂代谢;总胆固醇

DOI:10.14163/j.cnki.11-5547/r.2016.35.077

【Abstract】 Objective To compare changes of blood lipid levels before and after rehabilitation and recuperation in senile cardiovascular and cerebrovascular diseases patients, and to provide theoretical guidance for clinical application. Methods A total of 100 senile cardiovascular and cerebrovascular diseases patients in rehabilitation and recuperation all received targeted nursing intervention after admission. Self-control study was applied to compare total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, lipoprotein (a), and free fatty acid contents before and after rehabilitation and recuperation for comparative analysis by statistical software. Results Before rehabilitation and recuperation, the patients had total cholesterol as (6.04±0.35) mmol/L, triglyceride as (2.38±0.56) mmol/L, high density lipoprotein cholesterol as (0.86±0.34) mmol/L, low density lipoprotein cholesterol as (3.10±0.27) mmol/L, lipoprotein (a) as (409.12±56.11) mg/L, and free fatty acid as (1.45±0.25) mmol/L. After rehabilitation and recuperation, these indexes were respectively (5.35±0.23) mmol/L, (1.62±0.25) mmol/L, (1.20±0.31) mmol/L, (2.89±0.11) mmol/L, (301.31±24.85) mg/L and (0.75±0.29) mmol/L. Total cholesterol, triglyceride, low density lipoprotein cholesterol, lipoprotein (a), and free fatty acid contents were all obviously lower after rehabilitation and recuperation than those before rehabilitation and recuperation, while high density lipoprotein cholesterol content was much higher after rehabilitation and recuperation (P<0.05). Conclusion Rehabilitation and recuperation can improve lipid metabolism level in senile cardiovascular and cerebrovascular diseases patients. This method is worth clinical application and promotion.

【Key words】 Cardiovascular and cerebrovascular diseases; Rehabilitation and recuperation; Lipid metabolism; Total cholesterol

心脑血管疾病主要是指冠心病、高血压、动脉硬化、心肌梗死、脑出血、脑血栓等, 是由高血脂、高血糖、高粘血症及微循环障碍所引起的[1]。心脑血管疾病具有发病率高、死亡率高、致残率高、复发率高及并发症多的“四高一多”的特点。心脑血管疾病已成为威胁人类健康的重大杀手, 全世界每年死于心脑血管疾病的人数超过1500万人。高脂血症是血浆中的胆固醇、甘油三酯含量高于正常值, 多发于中老年人, 在中老年人常见疾病中约占70%左右。我国高血脂患者已超过1亿人, 高血脂常引起动脉硬化, 有研究表明高血脂可导致冠心病、心肌梗死、脑动脉硬化所致的脑血栓、脑梗死等[2]。……

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