连续血液滤过联合甘露醇治疗颅内高压合并肾功能衰竭的临床效果观察

2016-10-06于芳

中国卫生标准管理 2016年14期

于　芳

于芳

目的对连续血液滤过联合甘露醇治疗颅内高压合并肾功能衰竭的临床效果观察的探究。方法在2015年4月～2016年4月选取在我院进行治疗的颅内高压合并肾功能衰竭30例患者，将其分为对照组和观察组，对照组采用连续血液滤过的方法进行治疗；观察组采用连续血液滤过联合甘露醇方法进行治疗，观察采用连续血液滤过联合甘露醇治疗后的疗效。结果两组患者经治疗后，观察组治疗后在胱抑素浓度、颅内压及血肌酐浓度方面均低于对照组，差异有统计学意义（P＜0.05）；观察组在器官功能衰竭、脑疝及脑水肿的发生率低于对照组，差异有统计学意义（P＜0.05）。结论使用连续血液滤过联合甘露醇治疗颅内高压合并肾功能衰竭后，效果理想，提高患者的生存质量。

连续血液滤过；甘露醇；颅内高压；肾功能衰竭

【Abstract】

Objective To investigate the clinical effect of continuous hemofiltration and mannitol in treating intracranial hypertension combined with kidney failure. Methods 30 cases with intracranial hypertension combined with kidney failure in our hospital from April 2015 to April 2016 were selected as study objects. They were divided into control group and observation group. Control group was given continuous hemofiltration and observation group was given continuous hemofiltration and mannitol. Observe the clinical effect of continuous hemofiltration and mannitol in treating intracranial hypertension combined with kidney failure. ResultsAfter treatment，cystatin concentration，intracranial pressure and serum creatinine conceatrations of observation group were obviously lower than control group，the difference was statistically significant （P ＜ 0.05）. Occurrence rate of organ failure，cerebral hernia and encephaledema of observation group were lower than control group，the difference was statistically significant（P＜0.05）. Conclusion The application of continuous hemofiltration and mannitol in treating intracranial hypertension combined with kidney failure has significant effect and can improve life quality of patients.

【Key words】Continuous hemofiltration，Mannitol，Intracranial hypertension，Kidney failure

临床对颅内高血压合并肾功能衰竭的患者常采用连续血液滤过的方法进行治疗，在近些年的研究中发现对这些患者的治疗加之甘露醇的联合使用，效果会更佳［1］。连续血液滤过能够较好的调节体内血液的流动，同时对于调节甘露醇的脱水速度具有一定的作用。我院临床医生对此类患者采用联合方法治疗，获得较为满意的效果，现报道如下。