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比较七氟烷和丙泊酚联合瑞芬太尼用于短小腹腔镜手术的麻醉效果及对麻醉苏醒期的影响

2016-08-19韩耀明

中国实用医药 2016年22期

韩耀明

【摘要】 目的 研究分析七氟烷和丙泊酚联合瑞芬太尼用于短小腹腔镜手术的麻醉效果及对麻醉苏醒期的影响。方法 100例行短小腹腔镜手术的患者, 随机分为分析干预组与参照分析组, 各50例。参照分析组给予丙泊酚联合瑞芬太尼麻醉, 分析干预组给予七氟烷联合瑞芬太尼麻醉。对比分析两组患者的麻醉效果。结果 分析干预组患者插管后5、10 min的心率以及血压与参照分析组相比差异具有统计学意义(P<0.05)。分析干预组患者的麻醉苏醒期(6.22±1.05)min、进行自主呼吸的时间(4.23±1.04)min均短于参照分析组(10.94±1.56)、(8.83±1.54)min(P<0.05)。结论 七氟烷联合瑞芬太尼麻醉对短小腹腔镜手术患者的麻醉效果显著, 在临床上值得广泛推广。

【关键词】 七氟烷;丙泊酚;瑞芬太尼;短小腹腔镜手术;麻醉效果;麻醉苏醒期

DOI:10.14163/j.cnki.11-5547/r.2016.22.005

Comparison of anesthetic effects between sevoflurane and propofol combined with remifentanil in short laparoscopic surgery and influence on anesthesia recovery period HAN Yao-ming. Department of Anesthesiology, Liaoning Fushun Coal Mining Administration General Hospital, Fushun 113000, China

【Abstract】 Objective To research and analyze anesthetic effects between sevoflurane and propofol combined with remifentanil in short laparoscopic surgery and influence on anesthesia recovery period. Methods A total of 100 patients in short laparoscopic surgery were randomly divided into analysis intervention group and control analysis group, with 50 cases in each group. The control analysis group received propofol combined with remifentanil for anesthesia, and analysis intervention group received sevoflurane combined with remifentanil for anesthesia. Anesthetic effects were compared and analyzed between the two groups. Results The difference of heart rate and blood pressure in 5 and 10 min after intubation had statistical significance between the analysis intervention group and the control analysis group (P<0.05). The analysis intervention group had all shorter anesthesia recovery period as (6.22±1.05) min and autonomous respiration time as (4.23±1.04) min than (10.94±1.56) and (8.83±1.54) min in the control analysis group (P<0.05). Conclusion Combination of sevoflurane and remifentanil provides precisely anesthetic effect for patients in short laparoscopic surgery, and it is worth widely clinical promotion.

【Key words】 Sevoflurane; Propofol; Remifentanil; Short laparoscopic surgery; Anesthetic effect; Anesthesia recovery period

NEC是新生儿期的多发病, 发病率亦有上升趋势, 致死率亦较高, 是威胁新生儿健康的外科急症之一。随着基础科学与诊疗技术的迅猛发展, NICU的诊治水平也在不断进步, NEC在治疗过程中临床上应做到早诊断, 对于患儿愈后及减轻痛苦, 业界同仁已形成广泛共识。继诸如腹部X线平片、腹部超声及临床生物学检验等前期诊断方法后, I-FABP在血清中表达已成为早期诊断新生儿坏死性小肠结肠炎较为方便、可靠的生物学指标。现就本科研课题的研究成果报告如下。

1 资料与方法

1. 1 一般资料 选取本院儿科NICU 2012年1月~2015年11月收治的58例诊断为NEC患儿为实验组, 其中男41例, 女17例;发病时间为出生后2 h~36 d;出生体重890~3680 g, 平均出生体重(1898±308)g;其中Ⅰ级21例, Ⅱ级27例, Ⅲ级10例。以58例诊断为非NEC患儿为对照组, 其中嵌顿疝12例, 肠套叠8例, 肠梗阻16例, 阑尾炎14例, 其余8例为其他病种患儿。

1. 2 方法 以ELISA法测定患儿入院第1天及治疗第7天血清中I-FABP表达水平, 采用美国RD公司生产的ELISA试剂盒, 以450 nm 波长空白孔调零进行I-FABP测定, 具体操作方法严格按试剂盒说明书操作。……

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