糖尿病与抑郁共存的研究进展
2016-08-10凌枫王林创陈志刚
凌枫+王林创+陈志刚
摘 要 近年研究发现,糖尿病患者中抑郁症的患病率显著升高,而抑郁症患者中糖尿病的发生率也较正常人群显著提高,两者的共存给公共卫生和人类健康带来重大影响,而两者的早期发现和干预能显著降低其对人类健康的危害,故糖尿病与抑郁之间的关系也逐渐引起人类越来越多的重视。
关键词 糖尿病 抑郁症 患病率
中图分类号:R587.1/R749 文献标志码:A 文章编号:1006-1533(2016)14-0028-03
Research on the progress of coexistence of diabetes and depression
LING Feng, WANG Linchuang, CHEN Zhigang
(Longhua Community Health Service Center of Xiuhui District, Shanghai 200232, China)
ABSTRACT Recent studies have found that the prevalence rate of depression in the patients with diabetes significantly increased, and the incidence of diabetes is higher in the patients with depression than in the normal population. The coexistence of diabetes and depression has a significant impact on the public health and human health, and the early discovery and intervention can significantly reduce the harm to human health, therefore, the relationship between diabetes and depression has gradually attracted more and more attention.
KEY WORDS diabetes; depression; prevalence rate
糖尿病是一种全身代谢异常而导致的疾病[1]。随着社会的发展以及全球化进程的加快,糖尿病尤其是2型糖尿病在中国[2]、日本[3]等亚洲国家均有急剧增加趋势。据报道,2000年我国共有2型糖尿病患者2 000万例,2007年上升至4 000万例[4],成为严重影响我国人群健康的重要危险因素。近年来,研究发现糖尿病患者中抑郁症的患病率较正常人群显著升高,并且曾经患抑郁症的人群发生糖尿病的风险也较正常人显著提高。本文综述糖尿病与抑郁症共存的流行现状、发生机制、对患者的影响及干预措施。
1 糖尿病与抑郁共存的流行现状
国内外研究均提示,糖尿病患者尤其是老年糖尿病人群中抑郁的患病率较高,约27%的糖尿病患者伴有不同程度的抑郁症[5],其中老年糖尿病患者伴抑郁症的患病率为43.4%[6]。Engum等[7]研究发现,糖尿病患者中抑郁症发病率是正常人群的2倍。有研究应用抑郁自评量表(SDS)调查发现,有31.4%的糖尿病患者合并抑郁症,其中重度抑郁症占14.3%[8]。陈焕高[9]采用汉密尔顿抑郁量表调查发现,糖尿病患者中抑郁症的患病率为41.7%。……
