不同剂量孕激素治疗无排卵型月经失调对比分析
2016-07-16陈利华
陈利华
不同剂量孕激素治疗无排卵型月经失调对比分析
陈利华
目的 分析不同剂量孕激素在治疗无排卵型月经失调中的疗效。方法 选取2014年8月~2015年2月我院收治符合无排卵型月经失调诊断标准的患者80例,将所有患者随机分为A、B、C、D 4组,给予A组100 mg、B组200 mg、C组300 mg、D组400 mg口服黄体酮治疗,分析比较4组治疗效果。结果 对4组治疗疗效对比中,4组治疗疗效差异无统计学意义(P>0.05);在不良反应对比中,A组不良反应低于其他3组,差异具有统计学意义(P<0.05);经过治疗后,4组患者出血量均得到有效的控制,组间差异无统计学意义(P>0.05)。结论 不同剂量的孕激素在治疗无排卵型月经失调中均取得良好的治疗效果,考虑药物使用剂量安全性应给予患者最低剂量的孕激素,以达到安全、高效的临床效果。
孕激素;不同剂量;无排卵型月经失调
doi:10.3969/j.issn.1674-9316.2016.06.084
【Abstract】
Objective To analyze the treatment effect of menstrual disorder treated by different dose of progestational hormone. Methods To selected 80 cases of patients conformed to the standard of menstrual disorder at our hospital from August 2014 to February 2015,to randomly divided into the group A, B,C and D that 4 groups. The group A was given 100 mg, group B was 200 mg,the group C was 300 mg and the group D was 400 mg of the progesterone. To analyzebthe treatment effect. Results To compared the treatment effect,there was no statistical significance(P>0.05). To compared the adverse reactions,the group A was lower than the other three groups,there was statistical significance(P<0.05). After treatment,the amount of bleeding was controlled of them,there was no statistical significance (P>0.05). Conclusion That all has the favourable treatment effect of the different dose of progesterone for the menstrual disorder of anovulatory group,there should to given the lowest dose level of progestational hormone that considered the safety of using dose,so that to reach the clinic effect of safety and efficient.
【Key words】Progestational hormone,Different dose,Menstrual disorder of anovulatory group
女性月经失调是指体内雌孕激素紊乱或缺乏,导致女性排卵出现障碍,进而导致女性月经不规律,临床表现多为出血量多、持续时间长等症状,这些症状严重影响女性的生活质量。无排卵型月经失调则是指女性卵巢排卵异常,雌孕激素分泌不足,致使子宫内膜脱落异常、出现经期紊乱,经量增多,严重者甚至出现大出血症状。临床多采用孕酮类药物及雌激素治疗无排卵型月经失调[1]。本研究分析不同剂量孕激素在治疗无排卵型月经失调中的治疗疗效。现报告如下。
1 资料与方法
1.1 一般资料
选取2014年8月~2015年2月我院收治符合无排卵型月经失调诊断标准患者80例,将所有患者随机分为A、B、C、D 4组。……
