黄芳　林文英

[摘要] 目的 探讨盐酸氨溴索压缩雾化法治疗新生儿肺炎的效果。 方法 选取2014年4月～2015年6月在本院接受治疗的90例新生儿肺炎患儿作为研究对象，随机分为治疗组和对照组，各45例。对照组采用糜蛋白酶雾化法进行治疗，治疗组采用盐酸氨溴索压缩雾化法进行治疗。比较两组的临床症状消失时间、不良反应发生率及住院时间，并评价两组的临床疗效。 结果 治疗组的咳嗽停止时间、啰音消失时间、气促平稳时间、体温恢复时间及住院时间显著短于对照组，差异有统计学意义（P<0.05）。治疗组的总有效率为91.1%，显著高于对照组的75.5%，差异有统计学意义（P<0.05）。治疗组的不良反应发生率显著低于对照组，差异有统计学意义（P<0.05）。 结论 盐酸氨溴索压缩雾化法治疗新生儿肺炎效果显著，安全可靠，值得临床推广应用。

[关键词] 盐酸氨溴索压缩雾化法；糜蛋白酶雾化法；新生儿肺炎

[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-4721（2016）02（c）-0084-03

[Abstract] Objective To explore the effect of ambroxol hydrochloride compression nebulization method in the treatment of neonatal pneumonia. Methods 90 neonatal pneumonia patients in our hospital from April 2014 to June 2015 were selected and randomly divided into the treatment group and the control group，45 cases in each group.The control group was treated with chymotrypsin enzyme nebulization method，the treatment group was treated with ambroxol hydrochloride compression nebulization method.The disappearing time of clinical symptom，the incidence rate of adverse reaction and hospital stay in the two groups was compared，the clinical efficacy was evaluated in the two groups. Results Cough stopping time，rales disappearance time，shortness of breath stable time，body temperature recovery time and hospitalization time in the treatment group was shorter than that in the control group，with significant difference （P<0.05）.The total effective rate of the treatment group was 91.1%，which was higher than 75.5% of the control group，with significant difference （P<0.05）.The incidence rate of adverse reaction in the treatment group was lower than that in the control group，with significant difference （P<0.05）. Conclusion The effect of ambroxol hydrochloride compression nebulization method in the treatment of neonatal pneumonia is significant，safe and reliable，it is worthy of clinical promotion and application.

[Key words] Ambroxol hydrochloride compression nebulization method；Chymotrypsin enzyme nebulization method；Neonatal pneumonia

新生儿肺炎是临床上常见的小儿呼吸道疾病，形成原因复杂，感染率高，病情发展迅速，若不能及时控制病情，极易引起新生儿的呼吸衰竭甚至导致患儿死亡[1]，因此，临床上急需一种快速安全的治疗手段。盐酸氨溴索压缩雾化法与糜蛋白酶雾化法是目前临床上常用的治疗新生儿肺炎的有效手段。研究[2]显示，糜蛋白酶雾化法治疗新生儿肺炎具有一定的稀化痰液、改善肺炎作用，但是用药后会出现一定的过敏和呼吸道不适等现象。本研究选取本院的新生儿肺炎患儿作为研究对象，旨在探讨盐酸氨溴索压缩雾化法治疗新生儿肺炎的效果。

1 资料与方法

1.1 一般资料

选取2014年4月～2015年6月在本院治疗的90例新生儿肺炎患儿作为研究对象，随机分为治疗组和对照组，各45例。……