75例过敏性紫癜患儿的尿5项蛋白与肾脏病理的检测及分析
2016-02-05商树坤
商树坤
75例过敏性紫癜患儿的尿5项蛋白与肾脏病理的检测及分析
商树坤
【摘要】目的 分析75例过敏性紫癜患儿的尿5项蛋白及肾脏病理的检测结果。方法 以我院近1年收治的75例过敏性紫癜患儿作为观察组,以同期在我院进行体检的50例健康儿童作为对照组,所有患儿进行尿5项蛋白检测,同时观察组患儿另行病理检验。结果 观察组的尿5项蛋白含量指标均高于对照组,差异具有统计学意义(P<0.05)。观察组75例患儿肾穿刺活检均出现不同程度的肾脏损害。结论 过敏性紫癜患儿的尿微量白蛋白检测值高于健康儿童,临床若发现尿微量蛋白检测值高时,应立行肾穿刺活检,从而为HSPN的进一步诊断与治疗提供准确依据。
【关键词】过敏性紫癜;尿5项蛋白;病理改变
Objective To analyze the test results of 75 cases of allergic purpura in children with urinary protein and renal pathology. Methods In our hospital for nearly a year,75 cases of allergic purpura in children as the observation group,for medical examination. At the same period of 50 cases of healthy children as control group. All children with urinary five proteins detection,and to explore the further pathological examination of children. Results The observation group of 5 protein levels were higher than the control group,the difference was statistically significant(P<0.05). In the observation group,75 cases of renal biopsy showed different degrees of renal damage. Conclusion Urinary albumin in children with Henoch Schonlein purpura are higher than that of healthy children,in clinical if it is found that the urine trace protein test value is high,should be underwent renal biopsy,and provide accurate basis for HSPN further diagnosis and treatment.
【Key words】Henoch-schonlein purpura,5 kinds urinary protein,Pathological change
过敏性紫癜(Henoch-schonlein purpura,HSP)为儿科常见性的结缔组织疾病,临床症状为全身性小血管炎,会累及消化道、关节、皮肤、肾脏等多种组织[1]。而紫癜性肾炎(Henoch-schonlein purpura nephritis,HSPN)会严重影响HSP的预后。临床对于HSPN尚无统一诊断标准,一般以于HSP病程中出现蛋白尿或血尿作为诊断标准,但在诊断过程中容易忽略肾脏损害。为了对过敏性紫癜患儿的尿5项蛋白与肾脏病理的改变进行分析探讨,笔者对我院2015年1~12月收治的75例过敏性紫癜患儿的临床资料进行回顾性分析,现总结报道如下.
1 资料与方法
1.1 一般资料
以我院2015年1~12月收治的75例经尿5项蛋白与肾脏病理诊断为过敏性紫癜的患儿作为观察组,其中男43例,女32例;年龄为2~14岁,平均年龄为(7.3±2.6)岁;病程为2 d~5年,平均病程为(1.8±0.4)年。……
