几种红细胞和铁参数在儿童缺铁性贫血和溶血性贫血中的比较
2016-02-05林菊
林 菊
几种红细胞和铁参数在儿童缺铁性贫血和溶血性贫血中的比较
林 菊
【摘要】目的 探讨几种红细胞和铁参数在儿童缺铁性贫血和溶血性贫血中的应用。方法 择取3年内笔者所在医院就诊的缺铁性贫血患儿共50例,设其为研究组;择取同期就诊的溶血性贫血患儿50例,设其为对照组。两组患者于清晨取血后,用专用仪器中进行检测。结果 两组患儿在血红蛋白和sTfR两项指标差异无统计学意义(P>0.05);而在ZPP、RDW-SD与RDW-CV三项指标,研究组与对照组,差异有统计学意义(P<0.05)。结论 RDW用于反映红细胞的形态变异程度,ZPP是原卟啉与锌离子的结合产物,两种检测数据均可应用于诊断儿童缺铁性贫血和溶血性贫血。
【关键词】红细胞;铁参数;缺铁性贫血;溶血性贫血
Objective To investigate several red blood cells and iron parameters in children with iron deficiency anemia and hemolytic anemia. Methods Chose the three years,our hospital for treatment of iron deficiency anemia in children with a total of 50 cases as the study group. Selected the same period for treatment of hemolytic anemia in children in 50 cases as control group. Two groups of patients in the morning after taking blood,placed in a special instrument to detect. Results The two groups of children in hemoglobin and sTfR of two indicators had no statistical difference(P>0.05),and in the three indexes of ZPP,rdw-sd and rdw-cv,study group and the control group have significantly difference (P<0.05). Conclusion RDW is used to reflect the degree of morphological variation of red blood cells,ZPP is the combination of the porphyrin and the zinc ion,and the two kinds of detection data can be used in the diagnosis of children with iron deficiency anemia and hemolytic anemia.
【Key words】Red blood cells,Iron parameter,Iron deficiency anemia,Hemolytic anemia
常见的贫血可分为缺铁性贫血与地中海贫血,后者又可称之为溶血性贫血,前者多为人体缺少足量的营养元素而致病,而后者则多因遗传因素而致病[1]。两种贫血在一般的血常规检查中很难被清晰辨别,因此临床需要对具有较高特异性的参数进行对比检测[2]。鉴于铁元素是血红蛋白正常合成的必备微量元素,两种贫血在铁元素的缺乏与否有较大差异,本文试选择几种常见的铁元素参数与红细胞参数——红细胞分布宽度(RDW)、血清转铁蛋白受体(sTfR)、血锌原卟啉(ZPP),进行如下对比研究。
1 资料与方法
1.1 一般资料
择取2013年1月~2016年1月于笔者所在医院就诊的缺铁性贫血患儿共50例,设其为研究组;再择取同期于笔者所在医院就诊的溶血性贫血患儿50例,设其为对照组。……
