探讨血清孕酮与β-HCG联合检测在早期先兆流产治疗中的临床价值
2016-02-05何永娜
何永娜
探讨血清孕酮与β-HCG联合检测在早期先兆流产治疗中的临床价值
何永娜
【摘要】目的 对血清孕酮与β-HCG联合检测在早期先兆流产治疗中的临床价值进行分析和探讨。方法 选取我院2014年3月~2015年1月收治的50例早期先兆流产孕妇和50例流产患者,并以同期与我院进行孕期检查的50例正常孕妇为对照组,比较三组孕妇血清孕酮水平和β-HCG水平。结果 流产孕妇不同孕周的血清孕酮和β-HCG均低于正常孕妇和正常妊娠的先兆流产孕妇(P<0.05);血清孕酮12.2 ng/ml、β-HCG 5 000 IU/ml可作为先兆流产孕妇治疗是否有效的标志;血清孕酮与β-HCG联合检测敏感度高于血清孕酮和β-HCG单独检测(P<0.05)。结论 血清孕酮联合β-HCG水平是诊断早期先兆流产的重要指标,联合使用可有效提高检测敏感度。
【关键词】血清孕酮;β-HCG;早期先兆流产;临床价值
Objective To analyze the clinical value of combined detection of serum progesterone and beta-HCG in early threatened abortion. Methods In our hospital,50 cases of Early Threatened Abortion of pregnant women and 50 cases of abortion patients and in the same period and in our hospital for pregnancy examination of 50 cases of normal pregnant women as control group from March 2014 to January 2015,compared three groups of maternal serum levels of progesterone and hCG levels. Results The abortion of pregnant women in different gestational weeks of serum progesterone and hCG were lower than that of normal pregnant women and normal pregnancy threatened abortion pregnant women(P<0.05). serum progesterone 12.2 ng/ ml, hCG 5 000 IU / ml can be as a sign of pregnant women with threatened abortion. Serum progesterone and hCG combined detection of sensitivity washigher than that of serum progesterone and hCG detection alone(P<0.05). Conclusion The level of serum progesterone combined with beta-HCG is an important index for early diagnosis of threatened abortion, and the combined use of serum progesterone can effectively improve the detection sensitivity.【Key words】 Serum progesterone,β-HCG,Threatened abortion,Clinical value
早期先兆性流产已成为妇科的常见病和多发病,约有20%的孕妇可在孕期出现早期先兆性流产症状,为提高孕妇成功妊娠率,早期先兆性流产的诊断具有重要作用[1-3]。基于此,本研究以我院收治的部分孕妇为对象,对比分析血清孕酮与β-HCG联合检测的临床效果,现报告如下。
1 资料与方法
1.1 一般资料
选取2014年3月~2015年1月我院收治的50例先兆流产孕妇、50例流产孕妇和50例正常孕妇,年龄22~36岁,平均年龄(24.56±5.12)岁,平均孕周(8.51±1.41)周。3组孕妇年龄、孕周等一般资料的比较差异不具有统计学意义。
1.2 方法
空腹状态下抽取静脉血5 ml,分离血清,使用放射免疫分析法、电化学发光法、蛋白免疫印迹[4-6]检测3组孕妇的血清孕酮水平和β-HCG水平。……
