无创呼吸机联合纳洛酮治疗老年COPD并发呼吸衰竭患者的疗效观察
2016-02-05许俊山
许俊山
无创呼吸机联合纳洛酮治疗老年COPD并发呼吸衰竭患者的疗效观察
许俊山
【摘要】目的 研究无创呼吸机联合纳洛酮治疗老年COPD并发呼吸衰竭的临床效果。方法 抽取2014年7月~2015年11月我院收治的80例老年慢阻肺并发呼吸衰竭患者作为研究对象,随机分为两组,各40例。对照组采用常规治疗结合无创呼吸机方法,观察组在对照组治疗基础上,向患者静脉输注纳洛酮注射液,对比观察两组患者的临床疗效及住院期间再次插管率。结果 观察组治疗总有效率92.5%,再次插管率2.5%;对照组总有效率75.0%,再次插管率15.0%,两组相比,差异有统计学意义(P<0.05)。结论 无创呼吸机联合纳洛酮治疗老年COPD并发呼吸衰竭效果良好,再次插管率低。
【关键词】无创呼吸机;纳洛酮;COPD;呼吸衰竭
Objective To study the clinical effect of noninvasive ventilator combined with naloxone in the treatment of elderly patients with COPD complicated with respiratory failure. Methods From July 2014 to November 2015,chose 80 elderly patients in our hospital with chronic obstructive pulmonary disease and respiratory failure as research subjects,were randomly divided into two groups of 40 each. Control group with conventional therapy combined with non-invasive ventilation methods, observation group were treated with intravenous injection of naloxone based on control group.During hospitalization,clinical efficacy were observed,and comparing the reintubation rate. Results The total efficiency of the observation group 92.5%,reintubation rate was 2.5%,the control group of the total efficiency of 75.0%,reintubation rate of 15.0%, compared to the two groups,the difference was statistically significant (P<0.05). Conclusion Non invasive mechanical ventilation combined with naloxone in the treatment of elderly patients with COPD complicated with respiratory failure has good effect,low rate of re intubation.
【Key words】Noninvasive ventilator,Naloxone,COPD,Respiratory failure
慢性阻塞性肺疾病是一种由各种因素导致患者换气、通气功能障碍的慢性呼吸道阻塞性疾病的统称,病程长、多发于老年患者为该病的主要特征[1]。各项身体机能衰退的老年人,若不及时给予有效治疗,易引发呼吸衰竭并发症,严重者甚至导致患者死亡[2]。由于患者患病时间较长,呼吸肌长期处于紧张状态,加之营养不良,单纯使用常规药物进行治疗效果不佳。为提高治疗效果,我院特对老年COPD并发呼吸衰竭患者行无创呼吸机联合纳洛酮治疗,取得良好效果,现报道如下。
1 资料与方法
1.1 一般资料
抽取2014年7月~2015年11月我院收治的80例老年慢阻肺并发呼吸衰竭患者,随机分为两组,各40例。观察组男21例,女19例,年龄63~84岁,平均年龄(73.30±10.52)岁。……
