补脾肾活血法治疗慢性肾衰2~3期患者的疗效评价

杨晖李罗德汪香莲邹会徐玉琴刘慧琴

江西省景德镇市中医医院，江西景德镇333000

【摘要】目的：观察补脾肾活血法对慢性肾衰2-3期患者血肌酐及肾小球滤过率的临床疗效。方法：将80例患者随机分为治疗组和对照组，对照组40例，只用西医常规疗法和肾衰宁胶囊；治疗组40例，在西医常规疗法基础上采用补脾肾活血方治疗。结果:治疗组40例，显效24例，有效9例，无效7例，总有效率82.5%；对照组40例，显效10例，有效8例，无效22例，总有效率45.0%。两组疗效比较差异有高度统计学意义(P﹤0.01)。结论：补脾肾活血法能显著改善慢性肾衰2-3期患者肾功能，在改善患者临床症状方面有明显优势。

【关键词】补脾肾活血法；慢性肾衰；血肌酐；肾小球滤过率

【中图分类号】R692.5

【文献标志码】A

【文章编号】1007-8517(2015)21-0057-02

Abstract:Objective To observe the clinical effect of the treatment of spleen kidney and blood circulation on the serum creatinine and glomerular filtration rate in patients with chronic renal failure 2-3 phase. Methods 80 patients were randomly divided into treatment group and control group, 40 cases in control group, 40 cases treated with western medicine and traditional Chinese medicine.Results 40 cases of treatment group, 24 cases markedly effective, 7 cases effective, 9 cases ineffective, the total effective rate was 82.5%; the control group 40 cases, effective in 10 cases, effective in 8 cases, invalid 22 cases, the total effective rate was 45%. There were significant differences in efficacy between the two groups, P<0.01. Conclusion the spleen and kidney promoting blood circulation method can significantly improve the renal function of patients with chronic renal failure 2-3, and has obvious advantages in improving the clinical symptoms of patients.

Keywords:Spleen and Kidney;Chronic Renal Failure;Serum Creatinine;Glomerular Filtration Rate

收稿日期：(2015.07.29)

Tonifying Spleen and Kidney Activating Blood Circulation in the Treatment

of Chronic Renal Failure Clinical Evaluation of 2-3 Patients

YANG HuiLI LuodeWANG XianglianZOU HuiXU YuqinLIU Huiqin

Jingdezhen Hospital of TCM,Jingdezhen 333000,China

慢性肾功能不全常规治疗方法以西医对症及支持治疗为主，治疗目标是延缓疾病进展速度﹑尽量防止终末期肾病的到来。2014年2月至2015年2月期间，我院应用自拟补脾肾活血方治疗慢性肾衰2~3期患者40例，取得了较好的效果，现报道如下。

1资料与方法

1.1一般资料病例诊断标准参照《中药新药治疗慢性肾功能衰竭的临床研究指导原则》[1]诊断为慢性肾衰，辨证为脾肾虚衰，瘀血内结证；西医慢性肾衰诊断标准：①内生肌酐清除率(CCr)<80ml/min；②血肌酐(SCr)>133μmol/l；③有慢性肾脏疾病或累及肾脏的系统性疾病病史。具备任何两项即可诊断。诊断依据—主症：倦怠乏力，食少纳呆，面色晦暗，腰膝酸软，腰痛，畏寒肢冷；……