七叶皂苷钠联合太宁栓对混合痔患者术后的影响

赵敏1，王振军2*，许艳春3

(1.首都医科大学全科医学与继续教育学院、延庆医院普外科 北京 102100；

2.首都医科大学附属北京朝阳医院普通外科，北京 100020；3.中国人民解放军第251医院，北京 075000)

摘要：目的观察七叶皂苷钠联合太宁栓对混合痔术后患者的影响。方法选取2011年11—2014年2月我科收治混合痔患者191例，随机分为治疗组95例，对照组96例，2组患者均采用吻合器痔上黏膜环切(PPH)术治疗，术后给予二代头孢联合甲硝唑抗炎治疗，常规换药，治疗组在常规治疗的基础之上给予七叶皂苷钠联合太宁栓治疗,分别记录2组患者术后3、7 d肿胀消退情况并评分，采用疼痛视觉模拟评分(VAS)评价2组患者术后3、7、15 d疼痛缓解情况。结果治疗组患者术后3、7 d肿胀评分显著低于对照组(P<0.05)；2组术后3 d疼痛VAS评分比较差异无统计学意义(P>0.05),治疗组术后7、15 d疼痛VAS评分显著低于对照组(P<0.05);观察组伤口愈合时间显著快于对照组。结论七叶皂苷钠联合太宁栓可促进混合痔患者术后肿胀消退，减轻疼痛，利于伤口愈合。

关键词：混合痔；肿胀；疼痛；太宁栓；七叶皂苷钠

DOI::10.13463/j.cnki.jlzyy.2015.06.015

中图分类号：R657文献标志码： A

文章编号：1003-5699(2015)06-0581-03

基金项目:北京军区医疗成果项目(2009229)。

作者简介:赵敏(1979-)，女，硕士研究生，主治医师，主要从事肛肠外科疾病的研究。

收稿日期:(责任编辑：王丹2014-10-09)

*通信作者:王振军，教授，博士研究生导师,主任医师

Effect of aescinate combined with titanoreine suppository on patients after mixed hemorrhoid surgery

ZHAO Min1,WANG Zhenjun2*,XU Yanchun3

(1.The General Surgery Department,Yanqing Hospital,School of General Practice and Continuing Education

of Capital Medical University,Beijing 102100,China;

2.The General Surgery Department,Beijing Chaoyang Hospital Affiliated to Capital Medical University,Beijing 100020,China;

3.The 251th Hospital of the Chinese People’s Liberation Army,Beijing 075000,China)

Abstract:ObjectiveTo observe the effect of sodium aescinate in combined with titanoreine suppository on the patients after mixed hemorrhoid surgery.MethodsA total of 191 mixed hemorrhoid patients admitted in our department from November,2011 to February,2014 were enrolled in our study and randomized into the treatment group and the control group with 95 and 96 cases in each group,respectively.The patients in the two groups were treated with procedure for prolapse and hemorrhoids (PPH),given cephalosporin of the second generation and metronidazole for anti-inflammation after operation and routine dressing change.Based on the routine treatment,the patients in the treatment group were given sodium aescinate in combined with titanoreine suppository for reducing the swelling.The conditions of swelling reducing 3 and 7 days after surgery in the two groups were recorded and scaled,respectively.Visual analogue scale (VAS) was used to evaluate the conditions of pain relieving 3,7,and 15 days after surgery in the two groups.Results The swelling scores 3 and 7 days after surgery in the treatment group were significantly lower than those in the control group (P<0.05).The comparisons of VAS scores 3 days after surgery between the two groups were not statistically different (P>0.05);the VAS score 7 and 15 days after surgery in the treatment group was significantly lower than that in the control group (P<0.05).Observation group wound healing time was significantly faster than the control group.ConclusionAescinate combined with titanoreine suppository in treating with severe hemorrhoids has the advantages of swelling reducing,pain relieving,and wound healing.

Keywords:mixed hemorrhoid;swelling;pain;titanoreine suppository;aescinate

混合痔为肛肠科常见疾病，手术可有效治疗，但由于术后肛管和肛缘皮肤因局部血液和淋巴循环障碍，血管渗透压增加，组织液在间隙中储流过多，易导致患者发生伤口肿胀、疼痛等症状[1-3]。因此，有效改善及治疗术后伤口肿胀、减轻伤口疼痛是促进患者术后较好较快愈合的重要因素。……