静脉注射与口服铁剂治疗慢性肾功能不全肾性贫血的效果比较

闵群燕

江苏省太仓市第一人民医院肾内科，江苏太仓215400

[摘要]目的探讨静脉注射和口服铁剂治疗肾性贫血的效果。方法该院随机选取了2013年10月—2014年10月期间来治疗的60例肾性贫血患者作为研究对象，利用计算机软件把60例患者随机分成两组，观察组和对照组，每组30例患者。给予对照组口服铁剂治疗，观察组静脉注射治疗，比较观察两组治疗疗效。结果观察组治疗前的铁蛋白检测数据为（94.58± 12.86）ng/mL，对照组为（95.01±15.62）ng/mL，观察组治疗后的铁蛋白检测数据为（126.26±6.85）ng/mL，对照组治疗后为（102.52±8.92）ng/mL；观察组治疗后的Hb、Hct改善情况明显优于对照组；两组差异有统计学意义（P<0.05）。两组患者治疗中的不良反应差异无统计学意义（P＞0.05）。结论对肾性贫血患者使用静脉方式进行治疗安全、有效，可将患者临床病症有效改善，可推广治疗。

[关键词]静脉注射；口服铁剂；治疗；肾性贫血

[中图分类号]R452

[文献标识码]A

[文章编号]1674-0742（2015）10（a）－0040-03

[作者简介]闵群燕(1975.11-)，女，江苏太仓人，本科，副主任医师，主要从事肾内科工作。Comparison of the Effect Between Intravenous Injection of Ferralia and Oral Ferralia in the Treatment of Chronic Renal Insufficiency and Renal Anemia

Abstract[]Objective To investigate the effect of intravenous injection of ferralia and oral oral ferralia in the treatment of renal anemia.Methods Sixty patients with renal anemia treated in our hospital from October 2013 to October 2014 were selected as the subjects and randomly divided into two groups, the observation group and the control group with 30 cases in each by computer software.Patients in the control group were treated by oral ferralia and those in the observation group were treated by intravenous injection of ferralia.And the efficacy of the two groups was observed and compared.Results Before treatment, the ferritin level was (94.58±12.86) ng/mL in the observation group, and that was (95.01±15.62)ng/mL in the control group.After treatment, the ferritin level was (126.26±6.85) ng/mL in the observation group, and that was (102.52±8.92) ng/mL in the control group.The improvement of Hb and Hct level after treatment was much better in the observation group than that in the control group with statistically significant difference(P<0.05).The difference in the incidence of adverse reactions during the treatment between the two groups was not statistically significant(P>0.05).Conclusion For patients with renal anemia, intravenous injection of ferralia is safe, effective, which can effectively improve the clinical symptoms, so it is can be promoted.

收稿日期：（2015-06-25）

MIN Qun-yan

Department of Nephrology, Taicang City First People's Hospital of Jiangsu, Taicang, Jiangsu Province, 215400 China

[Key words]Intravenous injection; Oral ferralia; Treatment; Renal anemia

肾性贫血常见于肾功能不全，特别是尿毒症期患者，当前常用治疗方式为促红素治疗，但是经研究发现，部分肾性贫血患者因长期使用促红素，产生一定耐药性，因此疗效较差，这和缺乏铁有密切联系。多方面研究证明，对肾性贫血患者补充铁剂之后会将患者病情改善并可将使用促红素的剂量有效减少，因此在临床治疗中得到治疗医师的广泛推广[1-2]。为研究静脉注射和口服铁剂治疗肾性贫血的效果，该院随机选取了2013年10月—2014年10月期间来治疗的60例肾性贫血患者作为研究对象，现报道如下。

1　资料与方法

1.1一般资料