万红 张艳华 高军

[摘要] 目的 探讨心理干预对卵巢癌术后化疗患者焦虑和生活质量的影响。 方法 选取2012年 12月～2014年 12月在江西省人民医院行手术、化疗的84例卵巢癌病例，随机分成干预组和对照组，每组42例；干预组在化疗同时进行心理干预，而对照组仅接受常规卵巢癌护理措施；比较患者焦虑自评量表（self rating anxiety scale， SAS）和生活质量得分。 结果 干预组干预后的 SAS 得分显著低于对照组[（44.64±4.47） vs （52.25±4.12）]，而生活质量得分高于对照组[（79.55±5.84） vs （72.62±5.65）]，差异均有统计学意义（P<0.05）。 结论 心理干预能显著改善卵巢癌术后化疗患者的焦虑状况，提高对化疗的耐受性，提高患者生活质量。

[关键词] 卵巢肿瘤；化疗；心理干预；焦虑；生活质量

[中图分类号] R473.73 [文献标识码] B [文章编号] 1673-9701（2015）23-0143-03

Effect of psychological intervention on the anxiety and quality of life of patients with ovarian cancer postoperative chemotherapy

WAN Hong1 ZHANG Yanhua1 GAO Jun2

1.Obstetrics and Gynecology Department，the People's Hospital of Le'an County in Jiangxi Province， Le'an 344300， China； 2.Department of Gynecology， Jiangxi Provincial People's Hospital， Nanchang 330006， China

[Abstract] Objective To investigate the effect of psychological intervention on the anxiety and life quality of patients with ovarian cancer postoperative chemotherapy. Methods A total of 84 cases of ovarian cancer patients were involved， surgery and postoperative chemotherapy were suffered in department gynecology of Jiangxi provincial people's hospital from December 2012 to December 2014， they were randomly divided into intervention group and control group， 42 cases in each group. Psychological intervention were received in intervention group， while only routine ovarian cancer nursing measures were received in control group. The self rating anxiety scale（SAS） and quality of life scores were compared between two groups. Results The score of SAS in the intervention group was significantly lower than that in the control group[（44.64±4.47） vs （52.25±4.12）]， while the quality of life score was higher than that in the control group[（79.55±5.84） vs （72.62±5.65）]， the differences were statistically significant（P<0.05）. Conclusion Psychological intervention may be effective in improvement of anxiety significantly of ovarian cancer patients postoperative chemotherapy， may be effective in improvement the tolerance to chemotherapy and the quality of life of patients.

[Key words] Ovarian cancer； Chemotherapy； Psychological intervention； Anxiety； Quality of lif

卵巢癌是妇科常见肿瘤，进展迅速，疗效欠佳，已成为严重的医学和社会问题[1]。慢性心理应激是卵巢癌病因之一，并与肿瘤进展密切相关，且患者一经诊断，精神、心理压力增大，直接影响临床治疗、生活质量和预后[2]。近来年，通过妇瘤专家的不懈努力，采取手术与化疗相结合的手段，对提高患者生存率取得一定的成就。而针对心理应激的治疗有着重要作用，同时心理干预有利于患者树立积极的生活态度并配合治疗、改善负性情绪、提高对化疗的耐受性，进而改善生活质量[3，4]。本研究旨在观察心理干预对接受术后化疗的卵巢癌患者焦虑情况和生活质量的影响，现报道如下。

1 资料与方法

1.1 临床资料

选择 2012年 12月～2014年 12月在江西省人民医院行手术、化疗的84例上皮性卵巢癌（epithelial ovarian cancer，EOC）病例，中位年龄54.7岁（22～72岁）。采用随机数字表法将患者分为干预组和对照组，每组42例。两组患者的年龄、文化程度、手术病理分期、分化程度、组织学类型等资料比较差异无统计学意义（P>0.05）。入……