阿托伐他汀联合曲美他嗪治疗冠心病临床疗效观察
2014-08-11彭军
彭军
【摘要】 目的:观察冠心病采用常规治疗基础上加用阿托伐他汀联合曲美他嗪治疗的临床疗效。方法:将我院123例冠心病的患者随机分为综合组、对照A组和对照B组,每组41例。综合组采用常规治疗基础上加用阿托伐他汀联合曲美他嗪的综合疗法,对照A组采用常规治疗方法,对照A组采用常规治疗基础上加用曲美他嗪的治疗方法,对其疗效对比分析。结果:综合组总效率为92.68%;对照A组总有效率58.54%,对照B组总有效率75.61%,三组相比较均有显著的临床效果差异(P<005);三组患者治疗后的血脂变化均有较明显差异,具有统计学意义(P<0.05)。结论:冠心病患者通过常规疗法加用阿托伐他汀联合曲美他嗪的综合治疗具有较好治疗效果,且不良反应率底,值得临床使用。
【关键词】 阿托伐他汀; 曲美他嗪; 常规治疗; 冠心病; 疗效
【Abstract】 Objective: Observation of coronary heart disease by conventional therapy and clinical effect of Atorvastatin Combinedwithtrimetazidine treatment QuMei.Methods: 123 patients with coronary heart disease were randomly divided into combined group, A control group and B control group,each group of 41 cases.Comprehensive group usedroutine treatment plus comprehensive therapy with AtorvastatinCombined withtrimetazidine QuMei, control group A with conventional treatment, the control group A with conventional therapy plus trimetazidine treatment method for QuMei, analysis of its curative effect.Results:total efficiency of 92.68%; control group A, the total efficiency of 58.54%, compared with B group, the total efficiency of 75.61%, compared with the difference between the three groups had significant clinical effect (P<0.05);blood lipid changes were inthe three groups after treatment were significantly different, with statistical significance (P<0.05).Conclusion: Patients with coronary heart disease by conventional therapy plustreatment with Atorvastatin Combined with trimetazidine QuMei has good treatment effect, and the rate of adverse reactions, which is worthy of clinical use.
【Key words】 atorvastatinQuMei in conventional treatment efficacy in patients with coronary heart disease
【中图分类号】R453 【文献标识码】A 【文章编号】1005-0019(2014)03-0026-01
冠心病是指冠状动脉出现供血不足所导致的心肌缺血、缺氧,而引发阵发性压榨性疼痛或以胸部闷压不适为特点的临床综合征,因好发于中老年,属于病死率较高的心脏疾病。本次调研以我院自2010年7月收入的123例冠心病患者的临床资料及治疗效果进行分析,现总结如下:
1 资料与方法
1.1 一般资料:选取2010年7月到2013年7月来我院就诊的123例患有冠心病的患者随机分为对照A组、对照B组和综合组,每组41组。所有患者治疗前进行血脂检查总胆同醇(TC)为(4.32±0.26)mmol/L,甘油三酯(TG)为(1.82±052)mmol/L,高密度脂蛋白(HDL-C)为(1.03±0.05)mmol/L,低密度脂蛋白(LDL-C)为(2.62±0.34)mmol/L,其中男72例,女51例,年龄46~74岁,平均年龄59.6岁,平均体重65.7kg,平均身高165.3cm,病程为0.5~6年;对照A组采用常规治疗方法,对照B组采用常规治疗加用曲美他嗪方法,综合组采用常规治疗加用阿托伐他汀联合曲美他嗪的联合疗法。三组患者的性别、年龄、体重、身高、临床症状等各方面无明显差异(P>0.05),无统计学意义,具有可比性。……p>