Evaluation of the Efficacy of 3.0T Magnetic Resonance Dixon Technique in the Diagnosing of Vertebral Osteoporosis/LIAO Jian， RUAN Jiugen，LIU Xiaofang， HU Rong， XIAO Qiong， SONG Ting. // Medical Innovation of

[Abstract] Objective： To investigate the eficacy of 3.OT magnetic resonance Dixon technique in the diagnosing of vertebral osteoporosis.Method： A total of 8O patients who complained lumbar discomfort were admitted to u People's Hospital from January2023to May 2O24 wereselected as the research subjects.Allof themunderwent dual-energy X -rayabsorptiometry （DXA） bone mineral density（BMD） examination and magnetic resonance Dixon imaging examination.According to the DXA measurement results，the patients were divided into the low bone mass group （T value gt; -2.5but lt; -1.0）， the osteoporosis group （T value ⩽ -2.5） and the normal group （T value ⩾ -1.0）. The signal intensity ratio （SIR） and fat fraction （FF） of phase and antiphase of double-echo of L_1-4 inthe three groups were calculated and compared.The correlation of SIR，FFand BMD （T value）were evaluated by Pearson correlation analysis.The receiver operating characteristic （ROC）curve was applied to evaluate the value of SIR and FF inthe diagnosis of osteoporosis and low bone mass.Result： Among the 8O patients，there were 30 cases in the low bone mass group，30 cases in the osteoporosis group and 2O cases in the normal group.There were statistically significant differencesin SIR，FF and T value among the three groups （ P lt;0.05）. FF in the osteoporosis group was significantly higher than that inthe lowbone mass group andthe normal group，andFFin the low bone mass group was significantly higher than that in the normal group，the diffrences were statistically significant （ P lt;0.05）.SIR and Tvalue in the osteoporosis group were significantly lower than those in the low bone mass group and the normal group，and SIR and Tvalue inthe low bone mass group were significantly lower than those in the normal group，the differences were statistically significant （ P lt;0.05）. Pearson correlation analysis showed that there was obvious positive correlations between SIRand Tvalue，and obvious negative correlation between FFand T value （Plt;0.05） .ROC curve analysis showed that the sensitivityand specificity of SIR andFF in the diagnosing of osteoporosisandlowbonemasswerebothrelativelyhigh （Plt;0.05） .Conclusion：3.OTmagneticresonanceDixon technique has high diagnostic efficiency for vertebral osteoporosis.SIR and FF of L_1-4 are correlated with BMD. Monitoring above indexes can help to evaluate the degree of osteoporosis.

[Key words] 3.OT magnetic resonance imaging Dixon techniqueVertebraeOsteoporosis

First-author'saddress：Departmentof Imaging Center，uPeople'sHospital，u 338ooo， doi：10.3969/j.issn.1674-4985..17.034

骨质疏松属于全身代谢性骨病，主要表现为骨量下降或丢失、骨组织微结构受损、骨脆性增加，有研究表明，该病受年龄、性别、激素水平等因素影响[1。本病早期无明显症状，随着病情进展，骨量不断损失，骨微结构进一步变化，可能导致脆性骨折等严重后果，极大影响患者生活质量，已成为世界范围内的重要公共健康问题[2-3]。临床诊断主要基于病史采集、骨密度（BMD）测定，其中BMD应用双能X线吸收法（DXA）测定[4，然而，DXA检查费用较高，且频繁检查可能存在一定辐射风险，对于早期无特定症状或高风险人群而言成本效益较低。因此采取适宜检查方式，加强对风险人群初筛，提高骨质疏松诊断效能十分重要。随着影像学检查在临床的广泛应用，磁共振技术对骨质疏松的定量评价已取得一定进展[5。磁共振Dixon技术为水-脂分离技术，属于磁共振成像方法，由于机体脂肪与水共振频率存在明显差异，利用自旋回波序列可单独提取水与脂肪信号，一次扫描可获得反相位、同相位、纯水相、纯脂相4组图像，相较于常规磁共振可进一步丰富图像信息，对组织脂肪定量有较高应用价值[6-7]。高鹏等[研究表明，磁共振Dixon技术可定量分析骨质疏松等骨骼肌肉系统性疾病所致脂肪含量异常。为进一步提升骨质疏松诊断敏感度，从而为早期预防与治疗提供可参考方案，本次研究主要探讨应用3.0T磁共振Dixon技术诊断椎体骨质疏松的临床效能。

1资料与方法

1.1一般资料

选取2023年1月一2024年5月新余市人民医院收治的80例主诉腰部不适患者为研究对象。……