Analysis of the Guiding Effect of Platelet AntibodyCombined with Coagulation Function Detection in Perioperative Blood Transfusion Therapy/CHEN Liwan， CHEN Zijun，MA Zuoyun. //Medical Innovation of China，2025，22（20）：124-127

[Abstract]Objective： To explore the guiding effect of platelet antibody combined with coagulation function detection in perioperative blood transfusion therapy.Method：The clinical data of 68 patients with perioperative bloodtransfusion in in Hospital ofthe Second Xiangya Hospital CSUfromMarch 2O23 to March 2024 were retrospectivelyanalyzed，and they were grouped according to different blood transfusion guidance methods. The control group （ n =34） received blood transfusion based on the results of coagulation function detection，and the observation group （ n =34） received blood transfusion guidance based on platelet antibody combined with coagulation function detection.The infusion conditions of blood components，the coagulation function before and 24 hours after blood transfusion， platelet corrected count increment （CCI） and the occurrence of complications were compared between the two groups.Result：There were no statistically significant diferences in platelet，red blood cell suspension，cryoprecipitate，fresh frozen plasma and total blood transfusion volume between the two groups （ Pgt; 0.05）.24 hoursafter blood transfusion，there were nostatistically significant differences in TT，PT，APTTand FIB between the two groups （ P_， gt;0.05）.1 h and 24 h after blood transfusion，the platelet CCI in the observation group were significantly higher than thosein the control group（ Plt;0.05） .There wasno statistically significant difference inthe incidence of complications between the two groups （Pgt;0.05 ）.Conclusion：Platelet antibody combined with coagulation function detection has guiding value in perioperative blood transfusion therapy and can improve platelet CCI.

[KeyWords] Perioperative period Blood transfusionPlatelet antibodyCoagulation function

First-author's address：Department of Blood Transfusion， in Hospital of the Second Xiangya Hospital CSU， in 541001， China doi： 10.3969/j.issn.1674-4985.2025.20.029

输血是临床上多用于治疗严重创伤、大型手术或急性大出血患者的常用手段，通过成分血输注能够快速补充患者体内缺乏的红细胞、凝血因子及血小板，改善携氧能力和凝血功能，挽救急危重症患者生命[1-2]。输血前评估患者的病史、实验室检查结果能够有效识别需要输血的患者，还能降低输血相关并发症发生风险；此外，输血前血型和交叉配血的评估能够预防输血不相容现象，提高治疗有效率和安全性[3。目前临床输血评估方法较多，输血指征评估可以帮助选择合适的血液制品，但需要综合考量多项实验室指标，评估时间较长，容易延误治疗时机[4。凝血功能指标检测用于评估出血性损伤患者的凝血功能，并指导输血治疗，通过提供客观的定量数据来快速评估患者的凝血功能[5]。但凝血功能指标易受药物作用、疾病状态而影响准确度，因此需要结合其他检测手段联合应用。血小板抗体检测能够明确患者体内是否存在抗体，帮助医生评估是否进行输血或选用合适的输血方式，降低输血治疗风险。本研究主要分析血小板抗体联合凝血功能检测在围手术期输血指导中的价值。

1资料与方法

1.1一般资料

回顾性分析中南大学湘雅二医院桂林医院2023年3月一2024年3月收治的68例围手术期进行输血治疗的患者的临床资料。（1）纳入标准： ① 入院后择期手术； ② 符合文献[7]中输血指征； ③ 治疗依从性良好，可与医护人员正常沟通； ④ 年龄18＼～65岁。（2）排除标准： ① 有血液系统疾病史；……