Effect ofPhloroglucinol Combined with Low-frequency Electrical Stimulation on Urination in Primipara of Postpartum Urinary Retention/ZHONG Jianling，CEN Zhenkao.//Medical Innovation of China，2025，22（20）：043-047

[Abstract] Objective： To study the effect of Phloroglucinol combined with low-frequency electrical stimulation on the urination of primiparas with postpartum urinary retention （PUR）.Method： A total of 80 primiparas with urinary retention afterdeliveryat Dongkeng Hospital of Dongguan from June 2O22 to May2O24 were prospectivelyselected and divided into control group and observation group according to the digital random table method，with 4O cases in each group.The control group was treated with intravenous injection of Phloroglucinol， whilethe observation group was treated with low-frequency electrical stimulationon the basis of the control group. The therapeutic efects and voiding functions before and after treatment of the two groups were compared.The time of the first spontaneous voiding，voiding volume，residual urine volume in the bladder，urodynamic indicators， occurrence of complications and patient satisfaction of the two groups after treatment were observed and recorded. Result： Comparedwith the control group，the observation group had earlierfirstspontaneous urination，less residual urinevolume in thebladderand moreurinevolume（ P lt;0.05）.After the treatment，thebladder pressure，urethral distribution pressure and maximum urinary flow rate during urine storage in both groups were higher thanthose in the control group，and those in the observation group were higher than those in the control group （ P lt;0.05）. After the treatment，the total effectiverateand the total satisfactionwith treatment intheobservation group were both higher than those in the control group （ P lt;0.05）.There wasno statisticallysignificant difference in the incidence of adverse reactions between the two groups （ P_* gt;0.05）. Conclusion： The effect of Phloroglucinol combined with low-frequency electrical stimulation inthe treatmentof PUR in primiparas is remarkable.Itcan significantlyimprove theurination function of parturients， increase their satisfaction， and has good safety.

[Keywords] PhloroglucinolLow-frequency electrical stimulationPrimipara Urinary retention Jrination condition

产后尿潴留（PUR）是指生产后自主排尿困难或排尿后膀胱内残余尿量仍大于 150mL ，其作为初产妇经阴道分娩后的常见产褥期并发症，发生率可达 38%^[1-2] 。PUR不仅影响初产妇产褥期的生活质量，还会增加产妇尿路的风险，甚者可能引起尿失禁、膀胱直肠膨出及产后大出血等严重情况，对产妇的生理健康造成极大威胁[3]。目前，PUR的治疗方法仍以传统的诱导排尿法、盆底肌康复训练法等为主，虽有一定效果，但其疗效不能满足产妇PUR的临床应用[4。间苯三酚作为理想的解痉止痛药物，可作用于生殖泌尿系统的痉挛平滑肌，而对正常平滑肌的影响极小，且无抗胆碱作用，钱佳萌等的研究表明其联合电刺激治疗初产妇PUR具有显著效果。作为一种无创的治疗方法，低频电刺激可通过刺激产妇的神经和盆底肌肉以增强盆底肌张力，缓解膀胱肌麻痹，从而对PUR具有一定的治疗作用。因此，本研究采用间苯三酚联合低频电刺激对PUR产妇进行治疗，探究其治疗效果及对初产妇排尿情况的影响。

1资料与方法

1.1一般资料

前瞻性选取2022年6月—2024年5月东莞市东坑医院收治的80例PUR初产妇。纳入标准：（1）年龄22＼～32岁；（2）第一次怀孕并经阴道分娩；（3）产后 6～8h 无法自主排尿，或尽力排尿后膀胱内残余尿量仍 gt;150mL^[7] ；（4）自愿参与本研究。排除标准：（1）合并尿道感染、尿道梗阻等其他泌尿系统疾病；（2）合并严重心、肝、肾等器官病变；（3）中途退出／转院。以随机数字表法分为对照组及观察组，各40例。患者或者患者家属知情同意本研究，本研究经东莞市东坑医院医学伦理委员会批准。……