卢涛 陆政阳 蒙延海 朱昌盛 吴子宁 王水云

摘要：目的 分析2018至2022年肥厚型心肌病的研究进展和热点话题。方法 检索Web of Science核心合集数据库，纳入2018年1月1日至2022年12月31日发表的肥厚型心肌病相关文献，进行文献计量学分析。结果 共纳入6355篇文献，平均被引频次7次，2021年出版文献最多，为1406篇。VOSviewer软件分析显示，肥厚型心肌病相关的猝死研究，特别是磁共振心肌延迟强化对猝死的预测价值是目前的热点话题，此外基因检测和新药mavacamten研究也成为一大热点。美国是目前肥厚型心肌病发文量和文献被引频次最多的国家，中国学者发文量位居第2位，但高质量的研究成果较少。结论 猝死危险分层和预防仍是目前肥厚型心肌病领域重要和热点研究内容。国内学者应开展多中心合作，以提高研究成果的水平。

关键词：肥厚型心肌病；猝死；基因；mavacamten；文献计量学

中图分类号： R45  文献标识码： A  文章编号：1000-503X（2024）03-0377-07

DOI：10.3881/j.issn.1000-503X.15892

Bibliometrics Analysis of Studies on Hypertrophic Cardiomyopathy From 2018 to 2022

LU Tao，LU Zhengyang，MENG Yanhai，ZHU Changsheng，WU Zining，WANG Shuiyun

Adult Surgery Center，Fuwai Hospital，State Key Laboratory of Cardiovascular Disease，National Center for Cardiovascular Diseases，CAMS and PUMC，Beijing 100037，China

Corresponding author：WANG Shuiyun Tel：010-88396565，E-mail：wsymd@sina.com

ABSTRACT：Objective To analyze the research progress and hot topics in hypertrophic cardiomyopathy from 2018 to 2022.Methods The publications in the field of hypertrophic cardiomyopathy from January  2018 to December 3 2022 were retrieved from Web of Science core collection database and included for a bibliometric analysis.Results A total of 6355 publications were included，with an average citation frequency of 7 times.The year 2021 witnessed the most publications （1406）.The analysis with VOSviewer showed that the research on sudden death related to hypertrophic cardiomyopathy，especially the predictive value of late gadolinium-enhanced cardiac MRI in sudden death，was a hot topic.In addition，gene detection and the new drug mavacamten became hot research topics.The United States was the country with the largest number of publications and the highest citation frequency in this field.Chinese scholars produced the second largest number of publications，which，however，included few high-quality research results.Conclusions Risk stratification and prevention of sudden death is still an important and hot research content in the field of hypertrophic cardiomyopathy.Chinese scholars should carry out multi-center cooperation in the future to improve the research results.

Key words：hypertrophic cardiomyopathy；sudden death；gene；mavacamten；bibliometrics

Acta Acad Med Sin，2024，46（3）：377-383

肥厚型心肌病是一种常见的遗传性心脏病［1］，其临床表现具有高度异质性，包括心律失常、心力衰竭和心源性猝死等，治疗方式因其不同的临床表现而有所不同。肥厚型心肌病的研究热点随着对疾病认识的深入也在不断变化，了解国内外热点话题有助于掌握该领域的前沿趋势。文献计量学是基于已有文献体系，采用数学、统计学等计量研究方法，描绘、评价和预测文献研究结构、特征和规律的学科，被用于评估已发表文章及其引文的相互联系和影响［2］，以便把握研究方向。本研究采用文献计量学方法，对2018至2022年发表的肥厚型心肌病相关文献进行分析，为开展肥厚型心肌病更深层次的研究提供参考。……