占建军

[摘 要]目的 探究在带状疱疹患者中实施喷昔洛韦联合红光照射治疗的效果。方法 选取2021年10月-2023年12月麻城市皮肤病防治所收治的78例带状疱疹患者为研究对象，采用随机数字表法分为对照组和试验组，各39例。对照组实施喷昔洛韦治疗，试验组实施喷昔洛韦联合红光照射治疗，比较两组康复进程、心理情绪及疼痛度、睡眠质量及生活质量、临床疗效。结果 试验组止疱、结痂、止痛及痊愈时间短于对照组（P<0.05）；试验组治疗后SAS、SDS及NRS评分低于对照组（P<0.05）；试验组治疗后PSQI评分低于对照组、SF-36评分高于对照组（P<0.05）；试验组治疗总有效率为97.44%，高于对照组的84.62%（P<0.05）。结论 在带状疱疹患者中应用喷昔洛韦联合红光照射治疗能加快患者康复进程，减轻患者疼痛程度，改善其不良情绪，进而提高患者提高生活质量，值得临床应用。

[关键词] 红光照射；喷昔洛韦；带状疱疹

[中图分类号] R752 [文献标识码] A [文章编号]1004-4949（2024）10-0046-04

Clinical Effect of Penciclovir Combined with Red Light Irradiation in the Treatment of Herpes Zoster

ZHAN Jian-jun

（Department of Dermatology， Macheng Third Peoples Hospital/Macheng Dermatology Prevention and Control Institute， Macheng 438300， Hubei， China）

[Abstract]Objective To explore the effect of penciclovir combined with red light irradiation in patients with herpes zoster. Methods A total of 78 patients with herpes zoster admitted to Macheng Dermatology Prevention and Control Institute from October 2021 to December 2023 were selected as the research objects. They were divided into control group and experimental group by random number table method， with 39 patients in each group. The control group was treated with penciclovir， and the experimental group was treated with penciclovir combined with red light irradiation. The rehabilitation process， psychological mood and pain degree， sleep quality and quality of life， and clinical efficacy were compared between the two groups. Results The time of blister， scab， pain relief and recovery in the experimental group was shorter than that in the control group （P<0.05）. After treatment， the scores of SAS， SDS and NRS in the experimental group were lower than those in the control group （P<0.05）. After treatment， the PSQI score of the experimental group was lower than that of the control group， and the SF-36 score was higher than that of the control group （P<0.05）. The total effective rate of treatment in the experimental group was 97.44%， which was higher than 84.62% in the control group （P<0.05）. Conclusion For patients with herpes zoster， penciclovir combined with red light irradiation can accelerate the rehabilitation process of patients， reduce the pain degree of patients， improve their adverse emotions， and improve the quality of life of patients， which is worthy of clinical application.

[Key words] Red light irradiation； Peniclovir； Herpes zoster

带状疱疹（herpes zoster）是一种临床高发的病毒性皮肤病，通常是由水痘-带状疱疹病毒感染所致，以皮肤疱疹及神经炎性病变为主要特征[1]。一般情况下，人体在感染水痘-带状疱疹病毒时不会立即发病，而是当患者免疫力下降时，在神经中休眠的水痘-带状疱疹病毒被激活，继而引发神经性疼痛及带状分布的疱疹[2]。临床针对带状疱疹通常采取抗病毒药物治疗，如喷昔洛韦乳膏，但仅凭抗病毒药物并不能达到预期，应积极联合其他治疗措施提升临床疗效[3，4]。有报道指出[5]，红光照射可通过光波刺激真皮下层，促进细胞新生，进而加快皮损修复。基于此，本研究结合麻城市皮肤病防治所收治的78例带状疱疹患者临床资料，旨在探讨红光照射联合喷昔洛韦治疗带状疱疹的效果，现报道如下。

1 资料与方法

1.1 一般资料 选取2021年10月-2023年12月麻城市皮肤病防治所收治的78例带状疱疹患者为研究对象，采用随机数字表法分为对照组（n=39）和试验组（n=39）。……