卡前列素氨丁三醇联合宫腔球囊放置术治疗产后出血的作用探讨
2024-01-21苏昌华刘润萍
苏昌华 刘润萍



【摘要】目的:探讨卡前列素氨丁三醇联合宫腔球囊放置术治疗产后出血的应用效果。方法:于2019年5月—2021年11月,以我院收治52例产后出血患者作为研究对象,按照随机数字表法分为对照组和观察组,对照组26例给予常规治疗,观察组26例给予卡前列素氨丁三醇联合宫腔球囊放置术治疗。结果:治疗后,观察组在产时出血量低于对照组(P<0.05);治疗后,观察组在不良反应情况低于对照组(P<0.05);治疗后,观察组的SAS评分、SDS评分低于对照组(P<0.05);治疗后,观察组总有效率高于对照组(P<0.05)。结论:我院对产后出血患者治疗中,采用卡前列素氨丁三醇联合宫腔球囊放置术治疗,治疗效果显著,值得临床推广和使用。
【关键词】卡前列素氨丁三醇;宫腔球囊放置术;产后出血
The effect of carboprost tromethamine combined with intrauterine balloon placement in the treatment of postpartum hemorrhage
SU Changhua, LIU Runping
Yang County Hospital of Traditional Chinese Medicine, Hanzhong, Shaanxi 723300, China
【Abstract】Objective: To investigate the effect of carboprost tromethamine combined with intrauterine balloon placement in the treatment of postpartum hemorrhage. Methods: From May 2019 to November 2021, 52 patients with postpartum hemorrhage admitted to our hospital were selected as the study subjects, and were randomly divided into a control group and an observation group according to the random number table method. The control group (26 cases) received routine treatment, and the observation group (26 cases) received carboprost tromethamine combined with intrauterine balloon placement. Results: After treatment, the observation group had lower postpartum bleeding volume than the control group(P<0.05). After treatment, the adverse reactions in the observation group were lower than those in the control group(P<0.05). After treatment, the SAS and SDS scores of the observation group were lower than those of the control group(P<0.05). After treatment, the total effective rate of the observation group was higher than that of the control group(P<0.05). Conclusion: In the treatment of postpartum hemorrhage in our hospital, the combination of carboprost tromethamine and intrauterine balloon placement has significant therapeutic effect, which is worthy of clinical promotion and use.
【Key Words】Carboprost tromethamine; Intrauterine balloon placement surgery; Postpartum hemorrhage
在妇产科领域,产后出血是一种常见的危险并发症,特别是在剖宫产和阴道分娩中,剖宫产的发生率更高。临床上主要表现为宫缩乏力性失血及大量流血[1]。该疾病的发生与产妇的子宫收缩能力下降、软产道裂傷、自身凝血功能障碍以及胎盘因素等多种因素有关,病情恶化迅速且具有高度危险性。目前临床上常用缩宫素或缩宫酶进行保守性止血,但因其具有一定副作用,限制了在临床应用范围。作为前列腺素F2α的衍生物,卡前列素氨丁三醇在肌内注射后能够发挥前列腺素的作用,从而刺激子宫的收缩,进而抑制血液的外流,达到治疗的效果。近年来,随着对该类药物认识不断提高,其在产科领域得到广泛应用并获得良好的临床疗效。然而,该药品在高剂量使用时可能会引发一系列严重的不良反应,因此按照临床推荐的剂量使用时,有时预期的疗效并不理想。近年来,随着剖宫产率增加及社会人口流动加剧,产后大出血发病率也随之上升[2]。……
