血清C反应蛋白、肝功能和心肌酶谱检测在轮状病毒感染性腹泻患儿中的意义
2024-01-21彭洁王小平陈军华李秋荣
彭洁 王小平 陈军华 李秋荣

【摘要】目的:分析血清C反应蛋白、肝功能和心肌酶谱检测在轮状病毒感染性腹泻患儿中的意义。方法:选取我单位2021年1月—2022年12月的80例轮状病毒感染性腹泻患儿为观察组,且选取我单位2021年1月—2022年12月的80例健康儿童为对照组。检测两组的血清C反应蛋白、肝功能和心肌酶谱。结果:观察组轮状病毒感染性腹泻患儿的血清AST、C反应蛋白和ALT水平明显高于对照组(P<0.05);观察组轮状病毒感染性腹泻患儿的血清α-HBDH、CK-MB、LDH和CK水平明显高于对照组(P<0.05)。结论:血清C反应蛋白、肝功能和心肌酶谱检测在轮状病毒感染性腹泻患儿中有较好的临床意义。
【关键词】C反应蛋白;肝功能;心肌酶谱;轮状病毒感染性腹泻
Significance of serum C-reactive protein, liver function and cardiac enzyme profile tests in children with rotavirus-infected diarrhea
PENG Jie1, WANG Xiaoping2, CHEN Junhua3, LI Qiurong3
1.Pucheng County Center for Disease Control and Prevention, Weinan, Shaanxi 715500, China;2.Ningqiang County Hospital of Traditional Chinese Medicine, Hanzhong, Shaanxi 724400, China;3.Tianjin Hospital of Ningqiang County, Hanzhong, Shaanxi 724400, China
【Abstract】Objective:To analyze the significance of serum C-reactive protein, liver function and cardiac enzyme profile tests in children with rotavirus-infected diarrhea. Methods:80 children with rotavirus-infected diarrhea in our unit from January 2021 to December 2022 were selected as the observation group, and 80 healthy children in our unit from January 2021 to December 2022 were selected as the control group. Serum C-reactive protein, liver function and cardiac enzyme profile were measured in both groups. Results:Serum AST, C-reactive protein and ALT levels in children with rotavirus-infected diarrhea in the observation group were significantly higher than those in the control group (P<0.05); The serum α-HBDH, CK-MB, LDH and CK levels in children with rotavirus-infected diarrhea in the observation group were significantly higher than those in the control group (P<0.05). Conclusion:Serum C-reactive protein, liver function and cardiac enzyme profile tests have good clinical significance in children with rotavirus-infected diarrhea.
【Key Words】C-reactive protein; Liver function; Cardiac enzyme profile; Rotavirus-infected diarrhea
輪状病毒感染性腹泻的主要症状为呕吐、低热、腹胀和腹泻等,病情严重的患儿甚至会由于脱水而死亡。婴幼儿因为机体的免疫系统和肠胃系统功能尚未发育完善,加上还没有建立正常的肠道菌群,机体一旦受到病原菌的入侵,很容易发生感染,从而引起腹泻[1]。轮状病毒感染不但会引起腹泻,而且能引发病毒血症,导致肝脏和心肌受到损伤[2]。因此,需要及早对轮状病毒感染性腹泻进行准确的诊断和有效的治疗。
1 资料与方法
1.1 一般资料
选取我单位2021年1月—2022年12月的80例轮状病毒感染性腹泻患儿为观察组,且选取我院2021年1月—2022年12月的80例健康儿童为对照组。观察组80例,男46例,女34例,年龄0.9~7.3岁,平均年龄(3.27±1.39)岁,病程2~19d,平均病程(6.25±1.47)d;对照组80例,男45例,女35例,年龄0.9~7.2岁,平均年龄(3.42±1.28)岁。两组的基线资料具有可比性(P>0.05)。
1.2 研究方法
两组均取3mL空腹静脉血,采取ELISA法检测两组的血清门冬氨酸氨基转移酶(AST)、C反应蛋白和丙氨酸氨基转移酶(ALT)水平,且采取全自动生化分析仪检测两组的血清α-羟丁酸脱氢酶(α-HBDH)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)和肌酸激酶(CK)水平。……p>
