李杰教授病症结合治疗肿瘤常用药对
2021-11-29许博文王贺平李杰曹璐畅
许博文 王贺平 李杰 曹璐畅
摘要 药对是中医药治疗肿瘤重要特色之一,以其組成精巧、加减灵活为著,同时可作为独立方药的运用,突显了中医专病专方的应用思维。“先辨病、再辨证、佐以辨症,三位一体”是李杰教授的诊治特点,在病症结合的基础上,依据个体化病症的不同,善用药对治疗常见肿瘤,临床疗效显著。现对李杰教授治疗肿瘤的常用药对进行总结概述,以期提高临床诊疗效果及指导临床应用,且药对的经验性应用与凝练,对中药新药研发有一定的促进意义。
关键词 病症结合;辨病;辨证;药对;肿瘤;新药研发;李杰
Abstract Couplet medicinals are one of the important characteristics of traditional Chinese medicine(TCM) in the treatment of tumor.Because of its delicate composition,flexible addition and subtraction,it can also be used as an independent prescription,highlighting the thinking of the special prescription of TCM.Professor LI Jie′s characteristics of diagnosis and treatment are “first differentiating diseases,then differentiating syndrome,assisting with differentiating symptom,three in one”.On the basis of the combination of diseases,according to the difference of individualized diseases,the effective use of couplet medicinals for the treatment of common tumors has a significant clinical effect.In this paper,Professor LI Jie′s commonly used couplet medicinals in the treatment of tumor are summarized,in order to improve the clinical efficacy and guide clinical application.The empirical application and condensation of couplet medicinals have certain promoting significance for the research and development of new drugs of traditional Chinese medicine.
Keywords Combination of diseases and symptom; Disease differentiation; Syndrome differentiation; Couplet medicinals; Tumor; New drug development; LI jie
中图分类号:R273文献标识码:Bdoi:10.3969/j.issn.1673-7202.2021.20.021
李杰教授是中国中医科学院广安门医院肿瘤科主任医师,医学博士,博士研究生导师,“首都中青年名中医”,在诊治消化系统恶性肿瘤(食管癌、胃癌、肝癌、肠癌等)、肺癌、乳腺癌、恶性淋巴瘤等方面积累了丰富的临床经验。针对肿瘤的复杂病机,李杰教授常在辨病与辨证相结合的基础上,随症善用药对。我们有幸侍诊抄方,现将其常用药对及运用经验归纳如下,以供同道临床借鉴。
1 药对及其应用
药对,又称对药,是以临床运用相对固定搭配成对的两味或三味中药组成,是在中医理论指导下,平衡中药性能,针对特定疾病或病机特征或证候特点,所形成的经验性用药组合。药对内的有效组合,使二者间的相互作用达到协同、制约以及增效减毒的特性[1]。得益于现代医学及药理学的发展,药理分析结果表明,部分中药具有抗肿瘤作用,使其应用范围进一步扩大,结合传统医家的临床实践,这种中药的成对搭配在肿瘤的治疗中日渐发挥着更大的作用。……
