邹海蓉 王惠 钟毓

摘  要：目的  探讨经皮注射黄体酮后不同时间段引起的皮下脂膜炎的超声声像图特征，以提高超声诊断水平。方法  收集2014年7月～2020年7月在重庆医科大学附属大学城医院行黄体酮注射保胎治疗后产生脂膜炎反应的62例患者临床及超声资料进行回顾性分析，以分析其声像图与就诊时间的演变关系。将上述患者的脂膜炎超声声像图类型分为高回声为主的结节硬化型、以无回声为主的液化型以及以强回声为主的钙化型，并按照不同检查时间段进行分组（即将其分为A、B两组（A组≤6个月，37例;B组>6个月，25例），就其声像图类型进行组内及组间比较。结果  62例黄体酮注射后患脂膜炎患者中，6个月内就诊者声像图表现以高回声结节硬化型为主，6个月后就诊者声像图表现以无回声的液化型为主，以强回声为主的钙化型少见，两组内及组间比较差异均有统计学意义（P<0.05）。结论  掌握这些声像图变化特征在诊治黄体酮注射所致的脂膜炎中具有一定的指导意义。

关键词：黄体酮注射;皮下脂膜炎;声像图特征

中图分类号：R816.95    文献标识码：A    文章编号：1009-8011（2021）-13-0001-03

Analysis of ultrasonographic characteristics in different clinical times of subcutaneous panniculitis caused by progesterone injection

ZOU Hai-rong  WANG Hui  ZHONG Yu

（Department of Ultrasnography， University Town Hospital of Chongqing Medical University， Chongqing， 401331， China）

Abstract： Objective  To investigate ultrasonographic characteristics in different periods of subcutaneous panniculitis caused by progesterone injection for improving ultrasonic diagnosis accuracy. Methods  From July 2017 to July 2020， a total of 62 cases with panniculitis reaction after progesterone injection， who were recruited into Chongqing Medical University Town Hospital， were included into this study for examining the relationship of their ultrasonographics with time. We divided the 62 cases' clinical data into two groups by the time： group A of less than six months（n=37）， and group B of more than six months（n=25）， in which ultrasonography showed three types： the high-level echo type，the echoless type，and the strong-level echo and type. Results  The ultrasonographic types of panniculitis reaction after progesterone injection differed in examination time， showing high-level echo in 6 months after progesterone injection，echoless after 6 months of progesterone injection. There were significant differences in both groups or between them（P<0.05）. Conclusion  Mastering these ultrasonographic characteristics is valuable for promptly diagnosis of subcutaneous panniculitis caused by progesterone injection， has a certain clinical guiding significance.

Keywords： Progesterone injection; Subcutaneous Panniculity; Ultrasonography

臨床中长期大剂量肌肉注射黄体酮进行黄体功能支持是妊娠早期先兆流产患者的常规保胎治疗方式之一，然而长期大剂量肌肉注射，其注射部位却易出现红肿、结节、瘙痒等反应，病理上表现为一种特殊人工性皮下脂膜炎[1-2]。所谓的人工性皮下脂膜炎是一组由人为因素导致皮下脂肪受到非自体物质的刺激后产生的非化脓性炎症累及皮下脂肪组织的异质性炎症性疾病，全身脂肪组织均可受累，尤以浅表皮下脂肪层及腹腔内脂肪多见[3-4]。临……