李燃 赵菊花

【摘要】 目的 对带状疱疹后遗神经痛患者用揿针联合加巴喷丁进行治疗，并观察其临床疗效及安全性。

方法 将80例带状疱疹后遗神经痛患者按随机数字表分为治疗组、对照组两组（每组40例），对照组采用加巴喷丁、甲钴胺、维生素B1治疗，治疗组在对照组治疗的基础上加用揿针治疗，治疗2周后评估疗效，并记下治疗过程中的不良反应。

结果 治疗 2周后，治疗组与对照组疼痛VAS评分比较差异有统计学意义（P<0.05）。治疗组总有效率为97.50%，对照组总有效率为 75.00%，两组总有效率比较差异有统计学意义（P<0.05）。两组均未出现严重的不良反应。

结论 揿针联合加巴喷丁能明显提高带状疱疹后遗神经痛的临床疗效，且安全可靠，值得临床推广。

【关键词】 揿针;加巴喷丁;带状疱疹后遗神经痛

中图分类号：R246.7   文献标志码：A   DOI：10.3969/j.issn.1003-1383.2021.09.010

Clinical observation of efficacy for thumb-tack needle for subcutaneous embedding combined with gabapentin in the treatment of postherpetic neuralgia

LI Ran， ZHAO Juhua

（Department of Dermatology， Nanchong Central Hospital， Nanchong 637000，  Sichuan， China）

【Abstract】 Objective To treat patients with postherpetic neuralgia by   thumb-tack needle for subcutaneous embedding combined with gabapentin， and to observe its clinical efficacy and safety.

Methods 80 cases of postherpetic neuralgia were randomly divided into treatment group （40 cases） and control group（40 cases）. The control group were treated with gabapentin， mecobalamin and vitamin B1， and based on which， the  treatment group were treated with thumb-tack needle for subcutaneous embedding. After 2 weeks of treatment， curative effects were evaluated， and side effects during the treatment were recorded.

Results After 2   weeks of treatment， there was statistically significant difference in    pain visual analogue scores （VAS scores） between the treatment group and the control group  （P<0.05）. The total effective rate of the treatment group and the control group were 97.50% and 75.00%， respectively， and the difference was statistically significant （P < 0.05）. There were no serious adverse reactions in both groups.

Conclusion Thumb-tack needle for subcutaneous embedding combined with gabapentin can significantly improve the clinical effect of postherpetic neuralgia， and it is safe and reliable， which is worthy of clinical promotion.

【Key words】 thumb-tack needle for subcutaneous embedding; gabapentin; postherpetic neuralgia

帶状疱疹是临床上一种水痘-带状疱疹病毒感染所致的常见皮肤病，常常侵犯人体的外周神经[1～2]。这种病毒可长期潜伏于机体脊髓神经后根神经节，当人体在疲劳、感染、免疫力下降时，病毒可再次复制活跃，侵犯人体皮肤、神经，产生炎症，诱发神经性疼痛[3～4]。临床上，60岁以上罹患带状疱疹的老年人在皮损消退后常常遗留不同程度的带状疱疹后遗神经痛（postherpetic neuralgia，PHN），且患者的疼痛程度会随着年龄的加大而加剧，严重危害患者身心健康[5～6]。针对此病症，目前国内外学者尝试了多种治疗方法，比如药物配合物理治疗、加用抗抑郁药物、局部神经阻滞[7]等，但是均具有一定不良反应，并且疗效不一。2019年6月～2020年6月，南充市中心医院皮肤科采用揿针联合加巴喷丁治疗PHN 40例，取得了良好的治疗效果，现报道如下。……