张红 郑淑敏 孙春亭 孙晶 蔡富强

摘要 目的：探討葆宫止血颗粒辅助促进产后子宫复旧的临床效果。方法：选取2019年8月至2020年8月德州市人民医院收治的产妇92例作为研究对象，按照随机数字表法分为对照组和观察组，每组46例。对照组常规使用缩宫素，观察组采取缩宫素+葆宫止血颗粒。比较2组子宫复旧效果、宫底高度变化、产后恢复情况指标、产后子宫三径之和、血红蛋白（HGB）以及红细胞计数（RBC）、不良反应。结果：观察组子宫复旧效果明显优于对照组（P<0.05）。产后3 d和4 d，观察组宫底高度低于对照组（均P<0.05）。观察组分娩后恶露持续时间、分娩后腹痛持续时间均短于对照组（均P<0.05）。2组产后42 d子宫三径之和均降低，观察组低于对照组（P<0.05）。2组产后7 d HGB、RBC均降低，但观察组数值均高于对照组（均P<0.05）。2组不良反应发生率比较差异无统计学意义（P>0.05）。结论：顺产的产妇使用葆宫止血颗粒，可有助于提升产后子宫的复旧效率，降低产后疼痛程度，促进子宫收缩。

关键词 葆宫止血颗粒;子宫复旧;分娩;恶露;缩宫素;宫底高度;产后恢复;平滑肌

Analysis of Clinical Effects of Baogong Zhixue Granules in Promoting Postpartum Uterine Involution

ZHANG Hong1，ZHENG Shumin1，SUN Chunting2，SUN Jing3，CAI Fuqiang1

（1 Department of Obstetrics and Gynecology，People′s Hospital of Dezhou City，Shandong Province，Dezhou 253000，China; 2 Department of Medicine and Equipment，Hospital of China Water Resources and Hydropower 13th Engineering Bureau，Dezhou 253009，China; 3 Department of Obstetrics and Gynecology，Dezhou Maternity and Child Health Hospital，Dezhou 253000，China）

Abstract Objective：To explore the clinical effects of Baogongzhixue Granules assisting in promoting postpartum uterine involution.Methods：A total of 92 cases of parturients who gave birth in the Department of Obstetrics and Gynecology of Dezhou People′s Hospital from August 2019 to August 2020 were selected asresearch objects.According to the method of random number table，the parturients were divided into 46 cases in the control group and 46 cases in the observation group.Women in the control group routinely used oxytocin，and the observation group took oxytocin+Baogong Zhixue Granules.The effects of uterine involution，the height change of the uterine fundus，the indicators of postpartum recovery，the sum of the three diameters of the postpartum uterus，hemoglobin and red blood cell count，and adverse reactions were compared.Results：The effects of uterine involution in the observation group was significantly better than that in the control group（P<0.05）.On 3 d and 4 d postpartum，the height of the fundus of the uterus in the observation group was lower than that in the control group（all P<0.05）.The duration of lochia after childbirth and the duration of abdominal pain after childbirth in the observation group were lower than those in the control group（both P<0.05）.The sum of the three diameters of the uterus in the 2 groups at 42 days postpartum decreased，and the values in the observation group were lower than those in the control group（P<0.05）.The hemoglobin and red blood cell counts of the 2 groups decreased on the 7th day after delivery，but the values of the observation group were higher than those of the control group（all P<0.05）.There were no statistically significant differences in the incidence of adverse reactions between the 2 groups（P>0.05）.Conclusion：The use of Baogong Zhixue Granules for normal parturient women can help improve the efficiency of postpartum uterine involution，reduce the degree of postpartum pain and promote uterine contractions.

Keywords Baogong Zhixue Granules; Uterine involution; Childbirth; Lochia; Oxytocin; Height of uterine fundus; Postpartum recovery; Smooth muscle

中图分类号：R714;R271.4文献标识码：Adoi：10.3969/j.issn.1673-7202.2021.17.020

子宫复旧是产妇的正常生理过程，医学上一般将其定义为分娩后42 d之内，人体的子宫恢复到未怀孕时的状态[1]。子宫复旧一般认为是十分正常的变化过程，但是部分产妇因为合并子宫肌瘤、胎盘残留或者发生产后抑郁等，导致子宫复旧过程受阻[2]。若产妇在分娩后21 d仍然存在恶露不尽或者子宫未出现正常的收缩，则定义为子宫复旧不全，该类患者常伴有血性恶露、持续腹痛等，属于妇产科较为棘手的疾病之一[3]。但是以往的研究数据显示，随着我国全面二胎政策的放开，发生子宫复旧不全的患者数量呈现逐渐增高的趋势[4-6]。在社会经济发展的大背景下，人们对于健康标准的要求逐年提高，改善子宫复旧不全的需要也愈加强烈，如何采用药物促进产妇的子宫复旧也成为值得探索的医学问题之一。……