陈继涢 叶岩荣 严大鹏

[摘要]住院患者单剂量发药不仅减轻人力资源投入，更能提高工作效率，提升医疗服务水平。但由于目前尚无明确标准文件对口服拆零药品进行质量控制及管理，因此严格把控拆零药品各环节，规范拆零操作对药品质量安全及临床用药安全意义重大。本文主要通过对本院全自动单剂量锭剂分包机管理方式、使用过程中分包机的优缺点及拆零药品相关管理环节的重点进行梳理，以期为拆零药品的管控提供思路及经验借鉴。

[关键词]住院药房;自动分包机;拆零药品;药品调剂

[中图分类号] R95  [文献标识码] A   [文章编号]2095-0616（2021）24-0018-05

Safety management of dismounted drugs from the fully automatic dispensing and packing machine at the inpatient dispensary of our hospital

CHENJiyun1YEYanrongYANDapeng1

1.Pharmacy Department， Zhongshan Hospital， Fudan University （Xiamen Branch）， Fujian， Xiamen 361015， China;

2.Pharmacy Department， Zhongshan Hospital， Fudan University， Shanghai 200032， China

[Abstract] Unit dose dispensing for inpatients not only reduces human resource input， but also improves work efficiency and medical service level. However， at present， there is no document clarifying the criterion of controlling and administering the quality of oral dismounted drugs. Therefore， it is of great significance to strictly control each link of dismounted drugs and standardize dismounting operations for drug quality safety and clinical medication safety. This paper mainly analyzed the mode of management of the full-automatic single dose pastill dispensing machine， the advantages and disadvantages of the dispensing and packing machine in use and the key points in the related links of the management of dismounted drugs， so as to provide ideas and experience reference for the control of dismounted drugs.

[Key words] Inpatient dispensary; Automatic dispensing and packing machine; Dismounted drug; Drug dispensing

隨着信息化发展及人民生活水平的提高，药品质量安全愈加受到重视。2021年习近平总书记在“十四五”规划中明确提出要推进数字化转型、智能化升级，数字化医院是我国现代医疗发展的新趋势[1-2]。住院药房承担全院住院患者口服药品的调配、核对、发放工作。现住院患者口服药品均为单剂量发放，传统的摆药调剂过程占用大量人力，难以适应现代化药学服务[3-5]。近年来，全自动药品分包机被越来越多的医院引入并投入使用[6-8]。

全自动药品分包机可减少人力资源投入，节约时间，提高工作效率，但目前主要存在的问题为药品包装上所标示保质期均为完整包装下药品的保存期限，而分包机拆零片剂均为拆除原包装的裸片形式，同时国内外对于拆零片剂的保存期限尚无明确的标准来界定，因此拆零片剂各环节的质量管控显得尤为关键[9-12]。……