赵明明

摘要：目的 探讨吲达帕胺联合氨氯地平治疗老年高血压合并冠心病的疗效。方法 将60例于2020年3月-2021年3月收治的老年高血压合并冠心病患者纳入研究，并以等量电脑随机法均分成AB两组。均予以两组患者氨氯地平治疗，B组添加吲达帕胺治疗，并对比疗效。结果 B组临床疗效、血压控制情况、心功能改善情况均优于A组，对比有统计学意义（P〈0.05）。结论 将吲达帕胺与氨氯地平联合应用到老年高血压冠心病患者的治疗中，可提升临床疗效，并助患者稳定血压及改善心功能，值得被应用推广。

关键词：吲达帕胺;氨氯地平;老年患者;高血压;冠心病;心功能;疗效

[Abstract]Objective To investigate the efficacy of indapamide combined with amlodipine in the treatment of elderly hypertension with coronary heart disease. Methods 60 cases of elderly patients with hypertension and coronary heart disease from March 2020 to March 2021 were included in the study，and they were randomly divided into AB group and ab group. Both groups were treated with amlodipine，while group B was treated with indapamide. Results the clinical efficacy，blood pressure control and improvement of cardiac function in group B were better than those in group A，and the comparison was statistically significant（P ﹤ 0. 05）. Conclusion the combination of indapamide and amlodipine in the treatment of elderly patients with hypertension and coronary heart disease can improve the clinical efficacy，stabilize blood pressure and improve heart function，which is worthy of promotion.

[Key words]indapamide;Amlodipine;Elderly patients;hypertension;Coronary heart disease;Heart function;curative effect

高血压会导致全身小动脉发生硬化，并且随动脉硬化积累会形成动脉硬化性血栓，并最终导致血管管腔狭窄，而当病理过程发生在心脏，就会导致心脏血管狭窄并形成冠心病【1】。一般来讲冠心病和高血压具有伴随性。而随着我国老龄化社会进程的加快，导致冠心病、高血压的发病率逐年上升，且二者合并的病例较为多见，因此治疗高血压冠心病也成为了现阶段的研究重点。本次纳入研究老年高血压冠心病患者60例，并于2020年3月-2021年3月开展医学研究，着重分析吲达帕胺与氨氯地平的联合疗效。现将详细内容进行如下报告：

1 资料和方法

1.1一般资料

经院内伦理委员会批准，将60例于2020年3月-2021年3月收治的老年高血压合并冠心病患者纳入研究，并以等量电脑随机法均分成AB两组。A组男女比例17：13，年龄均值（70.65±3.70）岁，病程均值（6.24±1.46）年。……