甲泼尼龙+抗生素治疗重症肺炎的药学研究
2021-09-10王莹
王莹


摘要:目的 甲泼尼龙+抗生素治疗重症肺炎的药学研究。方法 随机选取我院收治的重症肺炎患者80例作为实验对象,时间为2019年6月-2020年6月,依据治疗方法的不同分为2组,各40例。参照组接受抗生素治疗,观察组在参照组基础上接受甲泼尼龙治疗,对比两组的治疗效果、不良反应。结果 两组在治疗效果、不良反应的比对上有差异存在,观察组均优于参照组,有显著差异(P<0.05)。结论 甲泼尼龙联用抗生素的治疗方法疗效显著,且不良反应较少,值得进一步推广应用。
关键词:甲泼尼龙;抗生素;重症肺炎;药学研究
[Abstract]Objective To study the Pharmacognosy of methylprednisolone and antibiotics in the treatment of severe pneumonia. Methods 80 patients with severe pneumonia were randomly selected as the experimental subjects,the time was June 2019-june 2020. According to the different treatment methods,they were divided into two groups,40 cases respectively. The reference group was treated with antibiotics,the observation group received methylprednisolone treatment on the basis of the reference group,and compared the therapeutic effect and adverse reactions of the two groups. Results there were differences in the treatment effect and adverse reactions between the two groups,and the observation group was better than the reference group(P < 0.05). Conclusion the combination of methylprednisolone and antibiotics has a significant effect and less adverse reactions,which is worth further application.
[Key words]methylprednisolone;antibiotics;severe pneumonia;pharmaceutical research
重癥肺炎是常见病、多发病,罹患重症肺炎的患者除具有咳嗽、感染等表现外,还会出现持续性高热的情况,病情进展严重时甚至会导致全身中毒以及其他脏器损伤【1-2】。就临床实际而言,重症肺炎属于危重症的范畴,故临床治疗难度较大【3】。过往主要应用抗生素治疗的方法,其效果已被临床广泛证实,但在辅助用药的选择上,临床依旧存在有不同论点【4】。因此,临床应用甲泼尼龙是否有助于患者的治疗,便得到广泛关注。基于此,本次实验将围绕着甲泼尼龙+抗生素治疗重症肺炎的药学研究进行考量分析,报告如下:
1 资料和方法
1.1一般资料
选随机选取我院收治的重症肺炎患者80例作为实验对象,时间为2019年6月-2020年6月,依据治疗方法的不同分为2组,各40例。参照组男25例,女15例,年龄49-80岁,平均年龄(63.54±3.64)岁;观察组男27例,女13例,年龄49-81岁,平均年龄(64.07±3.82)岁;对比结果表明,两组一般资料不具备统计学意义(P>0.05),组间可比。纳入标准:参与本次实验患者均经影像学诊断确诊为重症肺炎;自愿加入本次研究。排……
