刘亚芬 李秀玲 赵丽华 马琳 赵振

【摘 要】 目的：观察针药联合治疗前庭性偏头痛的疗效及对血清降钙素基因相关肽（CGPR）的影响。方法：选择前庭性偏头痛患者90例作为研究对象，随机分为两组。对照组45例给予氟桂利嗪和普萘洛尔治疗，观察组45例在对照组基础上联合针灸治疗。连续治疗2周，对比两组治疗前后血清降钙素基因相关肽（CGPR）数据变化和中医证候积分。结果：与对照组比较发现，实验组效果显著，且其中医证候积分优于对照组，差异具有统计学意义（P<0.05）。结论：西药联合针灸治疗前庭性偏头痛疗效显著，可有效改善血清降钙素基因相关肽（CGPR）水平，值得临床推广应用。

【关键词】 前庭性偏头痛;血清降钙素基因相关肽;针灸疗法

【中图分类号】R747.2   【文献标志码】 A    【文章编号】1007-8517（2021）09-0120-03

Abstract：Objective To observe the effect of acupuncture combined with medicine on vestibular migraine and its effect on serum calcitonin gene-related peptide （cgpr）.Methods 90 patients with vestibular migraine in our hospital were randomly divided into two groups by computer. The control group of 45 patients received conventional western medicine flunarizine and propranolol these two kinds of drug treatment， the observation group of 45 cases in the western medicine flunarizine and propranolol on the basis of these two drugs combined acupuncture treatment. Continuous treatment for 2 weeks， the changes of serum calcitonin gene-related peptide （cgpr） data and TCM symptom scores were compared between the two groups before and after treatment.Results Compared with the control group， the effect of the experimental group was significant， and its TCM symptom score was better than that of the control group， the difference was statistically significant （P<0.05）.Conclusion Western medicine combined with acupuncture in the treatment of vestibular migraine has a significant effect， which can effectively improve the level of serum calcitonin gene-related peptide （cgpr）， which is worthy of promotion and application in the future clinical work.

Keywords：Vestibular Migraine; Serum Calcitonin Gene-related Peptide; Acupuncture Therapy

前庭性偏頭痛属于眩晕国际分类中的一种病症，在中医学中，对应为眩晕头晕伴或不伴偏头痛，发作时的临床症状不仅伴有偏头痛的相关症状，还会存在前庭症状眩晕恶心呕吐，同时也会出现怕光怕吵且容易出现烦躁，严重的时候还可能伴有轻度的耳鸣、恶心和呕吐[1]。这也是一种与单纯偏头痛病因相似的疾病，是人脑中与平衡和视觉相关的脑区血管-神经调节异常引起的疾病[2]。此外，前庭性偏头痛诱因也非常多，比如：睡眠时间不足、过度劳累、天气气温的变化、情绪低落、焦虑抑郁、强烈的视觉刺激、不健康的饮食等都可能成为诱发症状的因素[3]。且每个患有前庭性偏头痛的患者诱因都可能会不一样。笔者根据中医理论在常规西医治疗的基础上使用针灸治疗前庭性偏头痛患者取得满意疗效，现报告如下。……