李大勇

[摘要] 目的 探討腹腔镜胃癌根治术治疗老年进展期胃癌的临床疗效。 方法 选取于2018年7月至2019年9月来院治疗的老年进展期胃癌患者100例，随机分为对照组和试验组，每组各50例。对照组采用常规的手术治疗，试验组患者采用腹腔镜胃癌切除手术。对比两组患者的术中情况及术后指标、临床疗效、肿瘤标志物水平及并发症发生率。 结果 两组患者采用不同的手术方式治疗后，试验组患者的术中情况以及术后指标明显优于对照组，试验组患者术后并发症出现率明显低于对照组，试验组患者临床治疗总有效率明显高于对照组患者，试验组患者CEA水平明显高于对照组;试验组患者CA125、CA19-9水平明显低于对照组，差异有统计学意义（P<0.05）。结论 采用腹腔镜胃癌根治术对老年进展期胃癌患者进行治疗效果显著，有效减少术后并发症的发生，改善手术各项指标以及肿瘤标志物水平，值得临床借鉴。

[关键词] 腹腔镜;胃癌根治术;进展期胃癌;老年患者;临床作用;治疗效果

[中图分类号] R735.2          [文献标识码] B          [文章编号] 1673-9701（2021）12-0063-04

Clinical efficacy of radical laparoscopic surgery for gastric cancer in the treatment of advanced gastric cancer in the elderly

LI Dayong

Department of General Surgery， Jiamusi Hospital of Traditional Chinese Medicine in Heilingjiang Province， Jiamusi   154002， China

[Abstract] Objective To make an experimental analysis of the clinical effect of radical laparoscopic surgery for gastric cancer in the treatment of advanced gastric cancer in the elderly. Methods A total of 100 elderly patients with advanced gastric cancer treated in the hospital from July 2018 to September 2019 were selected and randomly divided into a control group and an experimental group， with 50 cases in each group. The control group was treated with conventional surgery， and the experimental group was treated with radical laparoscopic surgery for gastric cancer. The intraoperative conditions， postoperative indicators， clinical efficacy， tumor marker levels， and complication rate of the two groups were compared. Results After the two groups were treated with different surgical methods， the intraoperative conditions and postoperative indicators of the experimental group were significantly better than those of the control group. The postoperative complications of the experimental group were significantly lower than those of the control group. The total effective rate of clinical treatment and the CEA level in the experiment group was significantly higher than that of the control group. The levels of CA125 and CA19-9 of the experimental group were significantly lower than those of the control group. The difference in data comparison between the two groups was statistically significant（P<0.05）. Conclusion Radical laparoscopic surgery for gastric cancer is significantly effective in treating elderly patients with advanced gastric cancer， which effectively reduces the occurrence of postoperative complications， improves various surgical indicators and tumor marker levels， and is worthy of clinical reference.

[Key words] Laparoscopy; Radical laparoscopic surgery for gastric cancer; Advanced gastric cancer; Elderly patients; Clinical effect; Therapeutic effect

进展期胃癌是指癌细胞已经蔓延至胃壁肌层以及浆膜层，不考虑患者病变部位的大小或是否出现转移现象[1]。这个时段的胃癌患者根据肉眼可见的病变位置形态分为息肉型、浸润型以及溃疡型[2]。据相关临床统计，在我国13年时期，患有进展期胃癌的老年患者达到了大约1300万人口，占我国总人数的10%左右，同时每年的胃癌发病人数约达到四十万人左右。进展期胃癌的老年患者由于体质等原因，给手术治疗造成了一定程度的困难，因此如何有效的治疗老年进展期胃癌患者是一个至关重要的问题[3]。本文针对治疗老年进展期胃癌患者采用了腹腔镜胃癌根治术进行实验，旨在找出更有效的治疗方法。……