曹建平 何松彬 蔡礼松 胡佩延 戴方瑜

[摘要] 目的 探討舟山海岛地区口服药物结合手法复位治疗良性发作性位置性眩晕的临床疗效。 方法 选取2017年9月至2019年8月我院神经内科、康复医学科门诊及住院诊断为良性发作性位置性眩晕患者112例，根据所选择的治疗方法将其分为对照组和治疗组，每组各56例。对照组仅口服甲磺酸倍他司汀片，治疗组口服甲磺酸倍他司汀片联合手法复位。治疗周期为1周。1周后评价两组治疗效果。 结果 经治疗后，治疗组治疗总有效率为89.29%，明显高于对照组的57.14%，差异有统计学意义（P<0.05）。治疗前两组患者的眩晕症状评分比较，差异无统计学意义（P>0.05）;治疗1周后，两组患者的眩晕症状评分均较治疗前显著降低（P<0.05），且治疗后的治疗组眩晕症状评分显著低于对照组，差异有统计学意义（P<0.05）。 结论 单纯口服药物及联合治疗方案均能改善良性发作性位置性眩晕症状，口服倍他司汀片结合手法复位治疗方案疗效更优。

[关键词] 海岛地区;良性发作性位置性眩晕;手法复位;口服药物

[中图分类号] R24;R72          [文献标识码] B          [文章编号] 1673-9701（2021）07-0100-03

Clinical efficacy on oral medicine combined with manipulative reduction in the treatment of benign paroxysmal positional vertigo in Zhoushan Island area

CAO Jianping1   HE Songbin2   CAI Lisong1   HU Peiyan1   DAI Fangyu2

1.Department of Rehabilitation Medicine， Zhoushan Hospital in Zhejiang Province， Zhoushan   316021， China; 2.Department of Neurology， Zhoushan Hospital in Zhejiang Province， Zhoushan   316021， China

[Abstract] Objective To investigate the clinical efficacy of oral medication combined with manual reduction in the treatment of benign paroxysmal positional vertigo in Zhoushan Island area. Methods A total of 112 patients with paroxysmal positional vertigo from September 2017 to August 2019 were selected from outpatient and inpatient services of neurology department and rehabilitation medicine department of our hospital were selected. They were divided into the control group and the treatment group according the treatment chosen，with 56 patients in each group. The control group was given betastatin mesylate tablets only， and the treatment group was given betastatin mesylate tablets combined with manipulative reduction. The treatment cycle was 1 week. Treatment effect was evaluated 1 week later. Results After treatment，the total effective rate in the treatment group was 89.29%， which was higher than that of 57.14% in the control group， with significant difference（P<0.05）. There was no significant difference of the clinical symptoms score between the two groups before the treatment（P>0.05）. After 1 week of treatment，the clinical symptoms score of both groups decreased more significantly than that before the treatment（P<0.05）， and the clinical symptoms score in the treatment group was significantly lower than that in the control group， with significant difference（P<0.05）. Conclusion Both oral medication alone and combined treatment regimen can improve the symptoms of benign paroxysmal positional vertigo，and oral betastatin combined with manipulative reduction regimen is more effective.

[Key words] Island area; Benign paroxysmal positional vertigo; Manipulative reduction; Oral medicine

良性发作性位置性眩晕（Benign paroxysmal positional vertigo，BPPV）是臨床上常见的内耳自限性疾病，一般与体位变化有关，相关BPPV 年发病率为（10.7-600.0）/10 万[1-3]。目前 BPPV治疗方案包括药物、手术、手法复位、前庭康复等方法。本研究选择2017年9月至2019年8月在我院神经内科、康复医学科门诊及住院的诊断为良性位置性眩晕患者定位在后半规管耳石的临床资料，探讨口服药物结合手法复位治疗BPPV的临床疗效，现报道如下。

1 资料与方法

1.1 一般资料

选取2017年9月至2019年8月在我院神经内科、康复医学科门诊及住院的112例良性发作性位置性眩晕患者的临床资料，患者临床症状包括不同程度的反复眩晕不适、恶心呕吐、耳鸣、摇晃感、记忆力衰退、头部昏沉、心慌心悸等……