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RDW与急性ST段抬高型心肌梗死新发心房颤动的相关性分析

2021-04-29王占胜张颖齐霁

中国现代医生 2021年6期

王占胜 张颖 齐霁

[摘要] 目的 探讨RDW与急性ST段抬高型心肌梗死新发心房颤动(AF)的相关性,识别和发现急性ST段抬高型心肌梗死新发AF风险更多的危险因素。 方法 选取2016年2月至2018年12月我院心内科连续入选490例ST段抬高型心肌梗死患者,根据是否新发AF,对患者临床特征及相关血液检测指标RDW进行Logistic回归分析,筛选引起新发AF的危险因素。 结果 入选患者中,有新发AF者50例,无新发AF者440例。单因素分析显示,两组年龄、高血压史、心衰史Killip分级及RDW比较,差异有统计学意义(P<0.05)。Logistic回归分析显示,RDW OR=1.48(95%CI:1.13~2.37),年龄OR=1.57(95%CI:1.07~2.76),Killip分级OR=3.64(95%CI:2.12~7.38),血压 OR=1.85(95%CI:1.47~5.94)。 结论 RDW为急性ST段抬高型心肌梗死新发心房颤动的独立危险因素。

[关键词] 急性ST段抬高型心肌梗死;心房颤动;RDW;Killip分级

[中图分类号] R542.2          [文献标识码] B          [文章编号] 1673-9701(2021)06-0045-04

Correlation analysis of RDW and new onset of atrial fibrillation induced by myocardial infarction with the type of acute ST-segment elevation

WANG Zhansheng   ZHANG Ying   QI Ji

No. 2 Ward of Cardiology, Shenyang Fourth People′s Hospital, Shenyang   110031, China

[Abstract] Objective To explore the correlation between RDW and new onset of atrial fibrillation(AF) in myocardial infarction with the type of acute ST-segment elevation, and to identify and discover more risk factors for new onset of AF in myocardial infarction with the type of acute ST-segment elevation. Methods From February 2016 to December 2018, a total of 490 patients with ST-segment elevation myocardial infarction were continuously enrolled in the cardiology department of our hospital. According to whether there was new onset of AF, Logistic regression analysis was performed on the clinical characteristics of the patients and the relevant blood test index RDW, and the risk factors that caused new onset of AF was screened. Results Among the selected patients, 50 cases had new onset of AF and 440 cases had no new onset of AF. Univariate analysis showed that the differences in age, hypertension, heart failure, Killip grading and RDW between the two groups were statistically significant(P<0.05). Logistic regression analysis showed RDW OR=1.48 (95%CI: 1.13-2.37), age OR=1.57 (95%CI: 1.07-2.76), Killip grading OR=3.64(95%CI: 2.12-7.38), and blood pressure OR=1.85(95%CI: 1.47-5.94). Conclusion RDW is an independent risk factor for new onset of atrial fibrillation in myocardial infarction with acute ST-segment elevation.

[Key words] Myocardial infarction with the type of acute ST-segment elevation; Atrial fibrillation(AF); RDW; Killip grading

急性心肌梗死(Acute myocardial infarction,AMI)常伴有心律失常,亞急性期最常见的心律失常是心房颤动(Atrial fibrillation,AF)[1]。AF是一种常见的心律失常,随着年龄的增长,其患病率增高[2]。AF可以使急性冠脉综合征变得复杂,尤其是急性ST段抬高型心肌梗死(ST-elevation myocardial infarction,STEMI)。AF在急性心肌梗死患者中的发病率为10%~15%,通常会增加死亡率和脑栓塞的发生率。急性心肌梗死后新发AF是急性心肌梗死住院期间和长期死亡率的独立预测因素[3]。红细胞体积分布宽度(The red blood cell distribution width,RDW)是反映红细胞(Red blood cell,RBC)体积异质性的参数,其生理学范围在11%~15%之间[4]。大量的临床证据显示,除了RBC性疾病外,RDW还可以诊断和预测心血管性疾病,高RDW与急性和慢性心脑血管性疾病有关,如急性冠脉综合征、缺血性脑血管病、外周动脉血管病、心力衰竭及高血压等[5-6]。因此,本研究旨在对急性ST段抬高型心肌梗死患者血液中RDW进行分析,以识别和发现急性ST段抬高型心肌梗死新发AF风险更多的危险因素,为改善患者预后提供理论依据,现报道如下。……

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