阴纪伟

[摘要] 目的 观察氢氧化钙糊剂和樟脑酚治疗儿童牙病的效果及用药不良反应。 方法 选取2017年3月至2020年3月我院收治的儿童牙病患儿100例进行研究，随机分为对照组（50例）和干预组（50例），对照组选择樟脑酚进行根管消毒，干预组选择氢氧化钙糊剂进行根管消毒，比较两组的治疗效果、疼痛情况及药物不良反应发生情况。结果 干预组的治疗总有效率为98.00%，明显高于对照组的82.00%，差异有统计学意义（P<0.05）。干预组的Ⅰ级、Ⅱ级、Ⅲ级疼痛发生率明显低于对照组，差异有统计学意义（P<0.05）。干预组的药物不良反应总发生率为2.00%，明显低于对照组的22.00%，差异有统计学意义（P<0.05）。 结论 氢氧化钙糊剂治疗儿童牙病的效果明显优于樟脑酚，药物不良反应总发生率更低，安全有效，能更加彻底地清除根管中的细菌、坏死组织及毒素，减轻患儿的痛苦，促进其健康，值得推广应用。

[关键词] 樟脑酚;氢氧化钙糊剂;儿童牙病;药物不良反应

[中图分类号] R780.1          [文献标识码] A          [文章编号] 1673-9701（2021）06-0020-03

The effect of camphor phenol and calcium hydroxide paste in the treatment of children′s dental disease and adverse drug reactions

YIN Jiwei

Department of Stomatology， Maternal and Child Health Hospital of Inner Mongolia Autonomous Region， Hohhot  010020， China

[Abstract] Objective To observe the effect of calcium hydroxide paste and camphor phenol in the treatment of children′s dental disease and adverse drug reactions. Methods A total of 100 children with dental diseases admitted to our hospital from March 2017 to March 2020 were selected for the study. They were randomly divided into the control group （50 cases） and the intervention group （50 cases）. The control group chose camphor phenol for root canal disinfection. The intervention group chose calcium hydroxide paste for root canal disinfection. The treatment effect， pain and adverse reactions of the two groups were compared. Results The total treatment effective rate of 98.00% in the intervention group was statistically significantly higher than the 82.00% in the control group（P<0.05）. The incidence of grade Ⅰ， Ⅱ and Ⅲ pain in the intervention group were statistically significantly lower than that in the control group（P<0.05）. The incidence of adverse reactions in the intervention group was 2.00%， statistically significantly lower than 22.00% in the control group（P<0.05）. Conclusion Calcium hydroxide paste has a significantly better effect on children′s dental disease than camphor phenol. It has a lower incidence of adverse reactions. It is safe， effective， and can more thoroughly remove bacteria， necrotic tissue， and toxins in the root canal. It can alleviate the suffering of children and promote their health and is worthy of promotion and application.

[Key words] Camphor phenol; Calcium hydroxide paste; Children′s dental disease; Adverse drug reactions

臨床最常见的儿童牙病有乳牙牙髓病及根尖周炎等，多因牙髓发生感染所引起，临床主要表现为咬合痛、叩痛等症状，若患儿的病情严重，可发生牙龈瘘道，增加患儿的痛苦[1]。根治儿童牙病通常需要进行根管消毒，将感染的细菌与毒性物质清除掉，以确保彻底治愈根管。国内常用的根管消毒药物有甲醛甲酚及樟脑酚等，抗菌效果较好，但其容易引起患儿根尖组织超敏反应，造成根尖周炎[2]。有研究结果显示，氢氧化钙糊剂治疗儿童牙病效果明显，并且应用较为广泛，不良反应更少[3]。本研究对氢氧化钙糊剂和樟脑酚治疗儿童牙病的效果及药物不良反应进行研究分析，为治疗儿童牙病提供参考依据，现报道如下。

1 资料与方法

1.1 一般资料

选取2017年3月至2020年3月我院收治的儿童牙病患儿100例进行研究，随机分为对照组（50例）和干预组（50例）。对照组中男27例，女23例;年龄3～12岁，平均（6.78±2.14）岁;患牙前牙24颗，双尖牙14颗，后牙12颗。……