许静

【摘要】 目的：探討经脐单孔腹腔镜手术治疗卵巢良性肿瘤患者的效果及对卵巢功能的影响。方法：选取2018年11月-2020年6月本院收治的108例良性卵巢肿瘤患者，根据手术治疗方式的不同分为对照组和研究组，每组54例。对照组应用传统三孔腹腔镜手术治疗，研究组应用经脐单孔腹腔镜手术治疗。比较两组卵巢功能指标、临床效果、美容度、疼痛评分、炎症因子水平和血管内皮功能。结果：术前，两组LH、E2、FSH比较，差异均无统计学意义（P>0.05）;术后，研究组E2低于对照组，LH、FSH均高于对照组，差异均有统计学意义（P<0.05）。研究组住院天数、下床活动时间、胃肠功能恢复时间、手术时间、肛门首次排气时间均短于对照组，术中出血量少于对照组，差异均有统计学意义（P<0.05）。研究组美容度评分为（4.53±0.26）分高于对照组的（2.13±0.12）分，差异有统计学意义（P<0.05）。术前，两组疼痛评分比较，差异无统计学意义（P>0.05）;术后12、24、72 h，研究组疼痛评分低于对照组，差异均有统计学意义（P<0.05）。术前、出院前，两组IL-6、hs-CRP、NO、IL-8、ET水平比较，差异均无统计学意义（P>0.05）。结论：经脐单孔腹腔镜手术治疗良性卵巢肿瘤患者效果理想，可以改善临床效果以及卵巢功能，临床上应当进一步推广应用。

【关键词】 良性卵巢肿瘤 经脐单孔腹腔镜手术 卵巢功能

Transumbilical Single Port Laparoscopic Surgery in the Treatment of Patients with Benign Ovarian Tumors and Its Influence on Ovarian Function/XU Jing. //Medical Innovation of China， 2021， 18（28）： 072-077

[Abstract] Objective： To investigate the effect of transumbilical single port laparoscopic surgery in patients with benign ovarian tumor and its effect on ovarian function. Method： A total of 108 patients with benign ovarian tumor in our hospital from November 2018 to June 2020 were selected， and they were divided into control group and study group according to different surgical treatment methods， 54 cases in each group. The control group was treated with traditional three port laparoscopic surgery， and the study group was treated with transumbilical single port laparoscopic surgery. Ovarian function index， clinical effect， cosmetic degree， pain scores， inflammatory factor level and vascular endothelial function were compared between two groups. Result： Before surgery， there were no significant differences in LH， E2 and FSH between two groups （P>0.05）; after surgery， E2 in the study group was lower than that in the control group， while LH and FSH in the study group were higher than those in the control group， the differences were statistically significant （P<0.05）. The hospitalization days， ambulation time， gastrointestinal function recovery time， surgical time and first anal exhaust time in the study group were shorter than those in the control group， and the intraoperative blood loss in the study group was less than that in the control group， the differences were statistically significant （P<0.05）. The beauty score in the study group was （4.53±0.26） points， which was higher than （2.13±0.12） points in the control group， the difference was statistically significant （P<0.05）. Before surgery， there was no significant difference in pain scores between two groups （P>0.05）; 12， 24， 72 h after surgery， the pain scores in the study group were lower than those in the control group， the differences were statistically significant （P<0.05）. Before surgery and discharge， there were no significant differences in the levels of IL-6， hs-CRP， NO， IL-8 and ET between two groups （P>0.05）. Conclusion： Transumbilical single port laparoscopic surgery in the treatment of benign ovarian tumor patients has ideal effect， can improve the clinical effect and ovarian function， should be further popularized in clinical application.

[Key words] Benign ovarian tumor Transumbilical single port laparoscopic surgery Ovarian function

First-author’s address： Xiehe Jiangbei Hospital of Huazhong University of Science and Technology （Wuhan Caidian District People’s Hospital）， Wuhan 430010， China

doi：10.3969/j.issn.1674-4985.2021.28.018

在女性卵巢中，卵巢腫瘤属于较为常见的妇科疾病，大多数发生原因和身体因素、遗传因素有关，这种疾病发生后，主要的症状有：发热、腹部肿块、下腹牵拉痛或者坠痛、腹水等，会导致患者的生活质量明显下降，同时病情如果持续性的发展，还会转化成为癌变，导致生命安全受到威胁[1]。……