杨宝莲 袁源 郭梅兰

【摘要】 目的：探究傳统中药制剂湿毒散治疗失禁性皮炎的临床效果。方法：选取2018年9月-2020年8月本院因大小便失禁诱发的90例失禁性皮炎住院患者，采用随机数字表法分为对照组、常规组和观察组，每组30例。对照组采用常规皮肤、大小便清洗等治疗方法，常规组在对照组基础上给予氧化锌软膏外涂，观察组在对照组的基础上加用自制湿毒散。比较三组疗效、创面愈合时间和皮损消退时间，治疗前后的红肿面积和疼痛程度。结果：三组创面愈合时间和皮损消退时间比较，差异均有统计学意义（P<0.05）。观察组和常规组创面愈合时间和皮损消退时间均短于对照组，且观察组均短于常规组，差异均有统计学意义（P<0.05）。治疗前，三组红肿面积和疼痛评分比较，差异均无统计学意义（P>0.05）;治疗后，观察组和常规组红肿面积均小于对照组，疼痛评分均低于对照组，且观察组红肿面积小于常规组，疼痛评分低于常规组，差异均有统计学意义（P<0.05）。治疗后，三组红肿面积和疼痛评分比较，差异均有统计学意义（P<0.05）。观察组和常规组总有效率均高于对照组，且观察组高于常规组，差异均有统计学意义（P<0.05）。结论：传统中药制剂湿毒散能有效加快失禁性皮炎患者创面愈合和皮损消退，改善红肿程度和疼痛程度，提高临床疗效。

【关键词】 失禁性皮炎 湿毒散 传统中药制剂 皮损

Observation on the Clinical Efficacy of Traditional Chinese Medicine Preparation Shidusan in the Treatment of Incontinent Dermatitis/YANG Baolian， YUAN Yuan， GUO Meilan. //Medical Innovation of China， 2021， 18（28）： -165

[Abstract] Objective： To explore the clinical efficacy of traditional Chinese medicine preparation Shidusan in the treatment of incontinent dermatitis. Method： A total of 90 patients with incontinent dermatitis induced by fecal and urine incontinence in our hospital from September 2018 to August 2020 were selected， and they were divided into control group， routine group and observation group according to random number table method， 30 cases in each group. The control group was treated with routine skin， urine and feces cleaning and other methods， the routine group was treated with Zinc Oxide Ointment on the basis of the control group， and the observation group was treated with self-made Shidusan on the basis of the control group. The curative effect， wound healing time， skin lesion regression time， redness area and pain degree before and after treatment were compared among three groups. Result： There were statistically significant differences in wound healing time and skin lesion regression time among three groups （P<0.05）. The wound healing time and skin lesion regression time of the observation group and the conventional group were shorter than those of the control group， and those of the observation group were shorter than those of the conventional group， the differences were statistically significant （P<0.05）. Before treatment， there were no significant differences in redness area and pain scores among three groups （P>0.05）; after treatment， the redness area of the observation group and the conventional group were smaller than that of the control group， and the pain scores of the observation group and the conventional group were lower than that of the control group， and the redness area of the observation group was smaller than that of the conventional group， and the pain score of the observation group was lower than that of the conventional group， the differences were statistically significant （P<0.05）. After treatment， there were statistically significant differences in redness area and pain scores among three groups （P<0.05）. The effective rate of the observation group and routine group were higher than that of the control group， and the observation group was higher than that of the routine group， the differences were statistically significant （P<0.05）. Conclusion： Traditional Chinese medicine preparation Shidusan can effectively accelerate the wound healing and skin lesion regression time in patients with incontinent dermatitis， improve the degree of redness and pain， and improve the clinical efficacy.

[Key words] Incontinent dermatitis Shidusan Traditional Chinese medicine preparation Skin lesion

First-author’s address： Ganzhou Traditional Chinese Medicine Hospital， Ganzhou 341000， China

doi：10.3969/j.issn.1674-4985.2021.28.040

失禁性皮炎是皮肤暴露在尿液或粪液中导致发生肿胀、红斑、糜烂等皮肤局部炎症造成的损伤，可分为轻度、中度和重度三个等级[1-5]。……