张成丹 李梦琪 邓洋 杨瑾 欧阳晓勇

【摘 要】 目的：探析上自秦、汉，下迄现代（1986年）治疗疮疡病用药规律以供临床参考和借鉴。方法：选用《中医方剂大辞典》疮疡病篇所使用方剂，并归纳总结其性味归经及功效，运用Excel2013统计、TCM Miner对数据进行频次统计、关联规则分析，最后采用Cytoscape3.6.1对所得关联规则进行网络视图制作。结果：历代医家治疗疮疡时常用药物25味，多属清热和补益类药，性味多以苦寒、辛温、甘平，多归脾胃、肺大肠、肝胆经，关联规则支持度为8%以上主要常用药对分析得到：当归-金银花，当归-甘草，金银花-甘草，防风-黄芩，大黄-黄芩，黄芩-连翘，防风-连翘，当归-防风，当归-川芎，当归-人参，人参-黄芪，当归-连翘，黄芪-甘草。结论：古往医家治疗疮疡病以攻补兼施，消托并用为法，以清热解毒，化瘀消痈，兼补气血。

【关键词】 数据挖掘;中医方剂大辞典;疮疡病;用药规律

【中图分类号】R261   【文献标志码】 A    【文章编号】1007-8517（2021）22-0016-05

Analysis on the Medication Rule of Traditional Chinese Medicine Prescription Dictionary

in the Treatment of Sores and Ulcers Based on Data Mining

ZHANG Chengdan LI Mengqi DENG Yang YANG Jing OUYANG Xiaoyong*

The First Affiliated Hospital of Yunnan University of traditional Chinese medicine/Yunnan Provincial

Hospital of traditional Chinese medicine， Kunming 650032， China

Abstract：Objective to analyze the medication rule of sores and ulcers from Qin Dynasty and Han Dynasty to modern （1986） for clinical reference. Methods the prescriptions used in the chapter of sores and diseases in the dictionary of traditional Chinese medicine prescriptions were selected， and their properties， tastes， meridians and efficacy were summarized. The data were analyzed by Excel 2013 statistics and TCM miner， Finally， the network view of the association rules was made by using Cytoscape 3.6.1.Results The results showed that 25 kinds of drugs were commonly used in the treatment of sores and ulcers， most of them were heat clearing and tonic drugs， and the nature and taste were bitter cold， pungent and sweet， Most of them belong to the lung， spleen， stomach and liver meridians， and the support degree of association rules is more than 8%. The main commonly used drug pairs are： Angelica honeysuckle， angelica Glycyrrhiza， honeysuckle licorice， Fangfeng Scutellaria， rhubarb Scutellaria， Scutellaria forsythia， Fangfeng forsythia， angelica Fangfeng， angelica chuanxiong， Angelica ginseng， ginseng Astragalus， angelica forsythia， astragalus root. Conclusion in the ancient times， the treatment of sores and ulcers used both attack and tonic， and eliminate Tuo， in order to clear away heat and detoxify， remove blood stasis and carbuncle， and replenish qi and blood.

Keywords：Traditional Chinese Medicine; Chinese Medicine Dictionary; Drug Use Rules

瘡疡是指各种致病因素侵袭人体后引起的一切体表化脓感染性疾病的总称，疮疡多由毒邪内侵，邪热灼血，以致气血凝滞而成，是中医外科最常见的一类疾病，可分为急性和慢性两种[1]。

1 资料与方法

1.1 数据来源 收集、整理《中医方剂大辞典》[2]中治疗疮疡病篇所有方剂（外用方剂及某些无法找到主要药材的方剂除外）共324首。

1.2 纳入标准 ①所纳入方剂均为治疗疮疡病的方剂;②所纳入方剂均采用中药内服，有具体药物且现今仍能找到药材的方剂。

1.3 排除标准 ①所纳入方剂不适用于疮疡病的治疗;②外用剂型;③治疗无中药汤剂且无具体药物或药物不完整。……