李国平

[摘要] 目的 对比治疗糖尿病性视网膜病变疾病中眼底激光单用和联合雷珠单抗方法的效果以及其对完全吸收的影响。 方法 利用分组研究法对该院于2017年8月—2019年3月收治的50例患者进行研究，单一组患者行眼底激光治疗（n=25），联合组患者行眼底激光联合雷珠单抗治疗（n=25），对比两组患者最终治疗效果。 結果 联合组患者眼底吸收时间短于单一组，差异有统计学意义（P<0.05）;联合组患者治疗后视力恢复情况和眼压恢复情况均好于单一组，差异有统计学意义（P<0.05）;联合组患者治疗后不良反应发生率8.00%低于单一组不良反应发生率32.00%，差异有统计学意义（P<0.05）。 结论 治疗糖尿病性视网膜病变疾病中应用眼底激光联合雷珠单抗方案治疗效果显著，患者视力恢复情况较好，且眼部血压控制情况乐观，还能够促进患者的眼底出血和渗血吸收，故值得在临床医学中广泛应用。

[关键词] 眼底激光;雷珠单抗;糖尿病性视网膜病变

[中图分类号] R77          [文献标识码] A          [文章编号] 1672-4062（2020）08（b）-0186-03

[Abstract] Objective To compare the effect of laser fundus alone and combined ranibizumab in the treatment of diabetic retinopathy and its effect on complete absorption. Methods A group study was used to study 50 patients admitted to the hospital from August 2017 to March 2019. A single group of patients underwent fundus laser treatment （n=25）， and a combined group of patients underwent fundus laser combined with Leizhu Monoclonal antibody treatment （n=25）， comparing the final treatment effect of the two groups of patients. Results The fundus absorption time of the patients in the combined group was shorter than that in the single group， and the difference was statistically significant（P<0.05）; the visual recovery and intraocular pressure recovery of the patients in the combined group were better than that in the single group， and the difference was statistically significant（P<0.05）; the incidence of adverse reactions in the combined group after treatment was 8%， which was lower than that in the single group 32.00%，and the difference was statistically significant（P<0.05）. Conclusion The use of fundus laser combined with ranibizumab in the treatment of diabetic retinopathy has a significant effect. The patients vision recovery is good， and the blood pressure control of the eye is optimistic. It can also promote the patients fundus hemorrhage and oozing absorption. It is worthy of wide application in clinical medicine.

[Key words] Fundus laser; Ranibizumab; Diabetic retinopathy

当今，随着人口老龄化速度的增快，使得糖尿病疾病的发病率逐渐增多。糖尿病性视网膜病变是糖尿病疾病一种十分常见的并发症，根据相关学术发现，有10年以上糖尿病病史的患者视网膜出现病变的概率高达70%。糖尿病性视网膜病变并发症主要临床特征就是患者的视网膜微血管发生改变，从而造成患者视网膜出现慢性损伤，最终使患者出现视力模糊，严重的甚至还会导致患者出现失明[1]。临床中治疗该疾病的常规方法就是采用眼底视网膜激光光凝术治疗，该种方法能够最大程度的减低患者出现血管渗漏现象，同时还可以促进患者视网膜消肿。但是，单独使用该种方法却无法对患者视网膜新生血管形成产生抑制性作用。为了能够找寻出治疗该并发症的有效措施，该次以该院于2017年8月—2019年3月收治的50例患者为对象，对治疗糖尿病性视网膜病变疾病中眼底激光单用和联合雷珠单抗方法的效果以及其对完全吸收的影响进行详细分析，现报道如下。……