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局部应用消炎痛辅助治疗2型糖尿病患者牙周炎的临床分析

2020-10-13高荣张燕

中外医疗 2020年22期
关键词:消炎痛牙周炎牙周

高荣 张燕

[摘要] 目的 探究2型糖尿病牙周炎患者局部实施消炎痛的治疗效果。方法 随机选取该院自2018年9月—2019年9月期间收治的72例2型糖尿病牙周炎患者,采取抽签法随机分为试验组(n=36)与参照组(n=36),参照组患者实施单纯刮治治疗,试验组患者在参照组基础上实施局部应用消炎痛,对比两组患者治疗前后IL-6、GCF标本的PGE2、AL、SBI、GI及PD。结果 治疗后,试验组患者IL-6为(3.47±0.53)pg/L低于参照组的(4.68±0.73)pg/L(t=8.048,P=0.000),GCF标本的PGE2为(142.38±9.57)μg/L低于参照组的(205.41±10.33)μg/L(t=26.856,P=0.000),AL为(3.17±0.57)mm低于参照组的(4.53±0.63)mm(t=9.605,P=0.000),SBI为(1.29±0.27)%低于参照组的(2.18±0.30)%(t=13.231,P=0.000),GI为(0.39±0.19)低于参照组的(1.16±0.26)(t=14.365,P=0.000),PD为(3.19±0.32)mm低于参照组的(4.47±0.41)mm,数据差异有统计学意义(t=14.767,P=0.000)。结论 2型糖尿病牙周炎患者局部实施消炎痛可改善牙周炎症及各项牙周指标,提升治疗效果,值得推广。

[关键词] 2型糖尿病;牙周炎;消炎痛

[中图分类号] R5          [文獻标识码] A          [文章编号] 1674-0742(2020)08(a)-0055-03

Clinical Analysis of Local Application of Indomethacin as an Adjuvant Treatment for Periodontitis in Patients with Type 2 Diabetes

GAO Rong1, ZHANG Yan2

1.Department of Stomatology, Laigang Hospital, Jinan, Shandong Province, 271126 China;2.Medical Insurance Department, Laigang Hospital, Jinan, Shandong Province, 271126 China

[Abstract] Objective To explore the effect of indomethacin treatment in patients with type 2 diabetic periodontitis. Methods Randomly select 72 patients with type 2 diabetes and periodontitis treated in our hospital from September 2018 to September 2019 were randomly divided into a test group (n=36) and a reference group (n=36) by drawing lots. The patients in the group were treated with curettage alone, and the patients in the test group were treated with indomethacin on the basis of the reference group. The PGE2, AL, SBI, GI, and PD of IL-6 and GCF specimens were compared before and after treatment in the two groups. Results After treatment, the IL-6 in the test group was(3.47±0.53)pg/L, which was lower than (4.68±0.73)pg/L in the reference group(t=8.048, P=0.000). The PGE2 of the GCF specimen was (142.38±9.57)μg/L, which was lower than the reference group's(205.41±10.33)μg/L(t=26.856, P=0.000),AL was (3.17±0.57)mm lower than the reference group's (4.53±0.63)mm (t=9.605, P=0.000), SBI was (1.29±0.27)% lower than the reference group's (2.18±0.30)% (t=13.231, P=0.000), GI (0.39±0.19)% is lower than (1.16±0.26)% of the reference group (t=14.365, P=0.000), PD is (3.19±0.32)mm lower than (4.47±0.41) of the reference group (t=14.767, P=0.000)mm. The difference of the data was statistically significant. Conclusion Local application of indomethacin in patients with type 2 diabetic periodontitis can improve periodontal inflammation and various periodontal indicators, improve treatment effects, and is worth promoting.

综上所述,2型糖尿病牙周炎患者局部实施消炎痛可提升治疗效果,改善牙周炎症及各项牙周指标,值得推广。

[参考文献]

[1]  张蓓蓓,陈子根.牙周基础治疗对2型糖尿病伴慢性牙周炎患者的影响[J].现代实用医学,2017,29(12):1634-1635.

[2]  周园园.局部应用消炎痛辅助治疗2型糖尿病患者牙周炎的临床分析[J].糖尿病新世界,2019,22(12):180-181.

[3]  高纪东. 治疗2型糖尿病患者牙周炎的方法与影响疗效的相关因素[J]. 全科口腔医学电子杂志, 2017, 4(18):43-44.

[4]  林晓悦,曾今诚,蔡树玉.牙周炎非手术治疗对2型糖尿病伴慢性牙周炎患者血糖控制等效果分析[J].内科,2019,14(2):218-220.

[5]  朱海宇.牙周基础治疗对老年牙周炎合并2型糖尿病患者的疗效及其糖代谢的影响[J].中国继续医学教育,2017,9(3):68-69.

[6]  孙冬冬,徐玮,王雷.牙周基础治疗对老年牙周炎合并2型糖尿病患者的疗效及其糖代谢的影响[J].饮食保健,2016,3(18):16-17.

[7]  张蓓蓓,陈子根.牙周基础治疗对2型糖尿病伴慢性牙周炎患者的影响[J].现代实用医学,2017,29(12):1634-1635.

[8]  曲梦,王玲芳,郭伟伟, 等.牙周炎患者口腔健康素养与疾病严重程度的相关性分析[J].中华现代护理杂志,2019,25(6):770-773.

[9]  Sun Dongdong, Xu Wei, Wang Lei.Effect of Periodontal Ther apy on Geriatric Periodontitis Complicated with Type 2 Diabetes and Its Glucose Metabolism[J].Food & Health, 2016, 3(18): 16-17.

[10]  Lin Xiaoyue, Zeng Jincheng, Cai Shuyu.Effects of non-surgical treatment of periodontitis on blood glucose control in patients with type 2 diabetes and chronic periodontitis[J].Internal Medicine, 2019,14(2): 218-220.

[11]  孫建平.局部应用消炎痛辅助治疗2型糖尿病患者牙周炎的临床研究[J].糖尿病新世界,2016,19(9):85-86.

(收稿日期:2020-05-09)

[作者简介] 高荣(1983-),女,山东威海人,本科,主治医师,研究方向:口腔内科。

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