尚积海

[摘要] 目的 研究阿卡波糖片联合甘精胰岛素用于治疗糖尿病的临床疗效。方法 择取2018年1月—2019年3月期间于该院收治的86例糖尿病患者作为研究对象，将其按照入院顺序编号后均分为常规组和项目组，每组43例患者。常规组患者仅使用阿卡波糖片治疗，项目组患者则使用阿卡波糖片配合甘精胰岛素治疗，研究比较两组患者临床疗效。结果 项目组患者治疗后空腹血糖、餐后量血糖以及糖化血红蛋白水平下降程度均高于常规组，两组间差异有统计学意义（P<0.05）;项目组患者治疗总有效率为95.35%，较常规组患者高，组间差异有统计学意义（P<0.05）;项目组患者治疗不良反应发生率低于常规组患者，组间差异有统计学意义（P<0.05）。结论 治疗糖尿病应用阿卡波糖片联合甘精胰岛素药物联用治疗方案，能够有效控制患者血糖水平，降低不良反应，具有现实借鉴意义。

[关键词] 阿卡波糖片;甘精胰岛素;糖尿病;糖化血红蛋白

[中图分类号] R587.1          [文献标识码] A          [文章编号] 1672-4062（2020）06（a）-0008-03

[Abstract] Objective To study the clinical efficacy of acarbose tablets combined with insulin glargine for the treatment of diabetes. Methods 86 patients with diabetes admitted in the hospital from January 2018 to March 2019 were selected as the research object， and they were divided into a regular group and a project group after being numbered according to the order of admission. The patients in the conventional group were treated with acarbose tablets only， and the patients in the project group were treated with acarbose tablets combined with insulin glargine to study and compare the clinical efficacy of the two groups. Results After treatment， the fasting blood glucose， postprandial blood glucose and glycated hemoglobin levels of the project group were higher than that of the conventional group， and the difference between the two groups was statistically significant（P<0.05）; the efficacy in the project group （95.35%） was higher than the patients in the conventional group， the difference between the groups was statistically significant（P<0.05）; the incidence of adverse reactions of the patients in the project group was lower than that in the conventional group， and the difference between the groups was statistically significant（P<0.05）. Conclusion The combination of acarbose tablets and insulin glargine drug combination therapy for the treatment of diabetes can effectively control patients' blood glucose levels and reduce adverse reactions， which has practical significance.

[Key words] Acarbose tablets; Insulin glargine; Diabetes; Glycated hemoglobin

糖尿病屬于内分泌失常疾病，该病的发生与胰岛素抵抗有关。老年人患糖尿病的风险较高，糖尿病患者的血糖水平将会大幅上升，且随着病程的增加患者病情将会愈加严重。糖尿病中2型糖尿病患者占比较多[1]。糖尿病患者长期处于高水平状况下，患者极易发生神经性病变以及心脑血管疾病，将会严重危害患者身体健康。糖尿病患者需要严格控制饮食，同时配合降糖药物治疗用以维持血糖水平。临床中用以降低血糖的药物较多，研究发现长期使用一种降糖药物治疗管理血糖效果不理想，可联用药物治疗以提升血糖管理水平[2]。该文旨在研究阿卡波糖片联用甘精胰岛素治疗糖尿病的临床疗效，择取2018年1月—2019年3月期间于该院收治的86例糖尿病患者作为研究对象开展临床研究，现报道如下。……