陈国萍

摘要目的：研究睡眠障碍儿童血清25羟基维生素D水平的变化情况，以为儿童睡眠障碍的诊治提供依据。方法：选取2017年6至12月罗定市妇幼保建院的30例睡眠障碍患儿为观察组，同时期的30名健康儿童为对照组。比较2组患者的血清25羟基维生素D水平，并比较观察组不同病程及睡眠时间者的血清25羟基维生素D水平。结果：观察组的血清25羟基维生素D水平显著低于对照组，观察组中病程较长及睡眠时间较短者的检测水平显著低于病程较短及睡眠时间较长者，差异有统计学意义（P<005）。结论：睡眠障碍儿童的血清25羟基维生素D水平异常下降，且受到病程及睡眠时间的影响较大，提示儿童睡眠障碍应重视维生素D的有效补充。

关键词儿童睡眠障碍;血清25羟基维生素D水平;睡眠时间;病程

Study on the Change of Serum 25hydroxyvitamin D Levels of children with Sleep Disorders

Chen Guoping

（Maternity and Child Care Building of Luoding City in Guangdong Province，Luoding 527220，China）

AbstractObjective：To study the change situation of serum 25hydroxyvitamin D levels of children with sleep disorders，in order to provide evidence for the diagnosis and treatment of children with sleep disordersMethods：A total of 30 children with sleep disorders from June 2017 to December 2017 were chosen as the observation group，while 30 healthy children at the same time were chosen as the control groupThe serum 25hydroxyvitamin D levels of two groups were compared，and the serum 25hydroxyvitamin D levels of observation group with different course of disease and sleep time were compared tooResults：The serum 25hydroxyvitamin D levels of observation group was lower than that of control group，the detection levels of observation group with longer course of disease and shorter sleep time were significantly lower than those of children with shorter course of disease and longer sleep time，there were statistically significant differences（P<005）Conclusion：The serum 25hydroxyvitamin D levels of children with sleep disorders is with abnormal drop，and the influence of course of disease and sleep time for it is great，so the children with sleep disorders should pay attention to the effective supplementation of vitamin D.

KeywordsSleep disorders in children;Serum 25hydroxyvitamin D levels;Sleep time; Course of disease

中圖分类号：R7205文献标识码：Adoi：10.3969/j.issn.2095-7130.2020.06.036

儿童时期的睡眠质量对儿童健康成长以及发育情况有着重要影响，但是部分儿童存在睡眠障碍问题，不利于儿童的健康成长，可导致儿童出现生长发育迟缓、记忆力低下等[1]。注重对儿童睡眠障碍的研究分析，可为其早期干预提供依据。结合当前临床文献报道，儿童睡眠障碍受到较多因素影响，比如遗传因素、环境因素、生理性疾病等[23]。近年来有研究指出儿童睡眠障碍的发生同血清25羟基维生素D水平存在密切关系[4]。基于上述研究，本文将笔者2017年6至12月收治的30例睡眠障碍患儿纳入研究，与健康儿童进行对照分析，旨在为儿童睡眠障碍的诊治提供依据，现报道如下。

1资料与方法

11一般资料选取2017年6至12月罗定市妇幼保建院的30例睡眠障碍患儿为观察组，同时期的30名健康儿童为对照组。……