高冬娜 罗美瑄

摘要目的：分析健康体检人群中，绝经期女性睡眠时间与骨密度变化的相关性。方法：选取2019年1月至2019年12月联勤保障部队第九○九医院厦门大学附属东南医院体检科体检的健康绝经期女性500例作为研究对象。检测所有研究对象右侧跟骨的骨密度，采用问卷形式调查研究对象的每日总睡眠时长、夜间睡眠时长、入睡时间以及午睡时长，并进行统计分析。结果：每日总睡眠时长大于8 h、夜间睡眠时长大于6 h、入睡时间22：00前的绝经期女性骨密度异常发生率低于每日睡眠时长少于8 h、夜间睡眠时长小于6 h以及入睡时间22：00后的女性（P<005）;与午睡时长低于1 h与午睡时长大于1 h的绝经期女性比较，骨密度异常发生率差异无统计学意义（P>005）。将是否发生骨密度异常作为因变量，将每日总睡眠时长、夜间睡眠时长、入睡时间以及午睡时长作为自变量进行Logistic回归分析，结果显示每日睡眠时长少于8 h、夜间睡眠时长小于6 h以及入睡时间22：00后的绝经期女性发生骨密度异常的风险增加（P<005）。结论：睡眠时间与绝经期女性骨密度密切相关，睡眠时长过短、入睡时间过晚等均与绝经期女性骨量流失有关。

关键词绝经期女性;睡眠时间;骨密度

Correlation Between Sleep Time and Bone Mineral Density of Menopausal Women in Physical Examination Population

GAO Dongna，LUO Meili

（Department of health management of southeast Hospital Affiliated to Xiamen University，Xiamen 363000，China）

AbstractObjective：To analyze the correlation between sleep time and bone mineral density in menopausal womenMethods：A total of 500 healthy menopausal women from January 2019 to December 2019 in the physical examination department of were studiedThe bone mineral density of the right calcaneus of all subjects was measured，and the total sleep time，night sleep time，sleep time and nap time of the subjects were investigated by questionnaireResults：The incidence of abnormal bone mineral density in menopausal women who slept more than 8 hours a day，more than 6 hours at night，and fall asleep before 22：00 was lower than that in women who slept less than 8 hours a day，less than 6 hours at night，and fall asleep after 22：00（P<005）The incidence of abnormal bone mineral density in menopausal women who siesta less than 1 hour and who siesta more than 1 hour in menopausal women has no significant difference（P>005）Whether there is abnormal bone mineral density or not ss a dependent variable，the total sleep time per day，sleep time at night，sleep time and nap time were used as independent variables for logistic regression analysisThe results showed that women who slept less than 8 hours a day，less than 6 hours at night and fall asleep before 22：00 had an increased risk of abnormal bone mineral density（P<005）Conclusion：Sleep time is closely related to the bone mineral density of menopausal womenShort sleep time and late sleep time are related to the bone loss of menopausal women.

KeywordsMenopausal women; Sleep time; Bone mineral density

中圖分类号：R173;R68文献标识码：Adoi：10.3969/j.issn.2095-7130.2020.06.030

骨质疏松是骨量减少、骨质脆性增加的全身性骨疾病，受到年龄、性别、钙剂摄入等多种因素的影响。绝经期女性更容易发生，但骨密度变化与睡眠之间的关系尚未明确，本研究对此进行了初步研究，现报道如下。

1資料与方法

11一般资料选取2019年1月至2019年12月联勤保障部队第九○九医院厦门大学附属东南医院体检科体检的健康绝经期女性500例作为研究对象。年龄45～70岁，平均年龄（6281±567）岁，已婚481例，未婚19例。患者及其家属对本研究知情同意，并签署知情同意书。……