柯发东

[摘要] 目的 探析手術源性干眼患者实施临床干预措施的临床疗效。 方法 选取2018年1月～2020年1月在我院治疗的106例手术源性干眼患者为观察对象，按照随机原则分成对照组与干预组，每组53例。对照组患者予以常规治疗，干预组患者在对照组基础上予以玻璃酸钠滴眼液治疗与临床干预措施，分析比较两组患者临床疗效、治疗前后干眼症状评分、基础泪液分泌量、泪膜破裂时间。 结果 在临床疗效上，干预组总有效率为96.23%，对照组总有效率为83.02%，差异有统计学意义（P<0.05）。两组治疗后干眼症状评分均较治疗前降低，且干预组评分低于对照组，差异有统计学意义（P<0.05）。干预组基础泪液分泌量、泪膜破裂时间均明显优于对照组，差异有统计学意义（P<0.05）。 结论 手术源性干眼患者应用玻璃酸钠滴眼液治疗与临床干预措施的效果更加确切，能够有效减轻患者干眼症状，增强患者泪膜稳定性，值得临床推广应用。

[关键词] 手术源性干眼;玻璃酸钠滴眼液;临床干预措施;干眼症状

[中图分类号] R771          [文献标识码] B          [文章编号] 1673-9701（2020）16-0070-03

Study on the curative effect of clinical interventions for patients with operation derived dry eye

KE Fadong

Department of Ophthalmology， the Seventh People's Hospital of Changzhou City in Jiangsu Province， Changzhou 213003， China

[Abstract] Objective To explore the clinical effect of clinical interventions for patients with operation derived dry eye. Methods 106 patients with operation-derived dry eye treated in our hospital were selected as observation objects from January 2018 to January 2020. They were divided into the control group and the intervention group according to random principles， with 53 cases in each group. Patients in the control group were given conventional treatment. Patients in the intervention group were treated with sodium hyaluronate eye drops on the basis of treatment of the control group and clinical interventions. The clinical efficacy， dry eye symptom scores before and after treatment， the amount of basal tear secretion and tear film rupture time were analyzed and compared between the two groups. Results There was significant difference in the total effective rate between the intervention group（96.23%） and the control group（83.02%） （P<0.05）. The dry eye symptom scores of the two groups after treatment were lower than those before treatment. The score of the intervention group was lower than that of the control group， and the difference was statistically significant（P<0.05）. The amount of basal tear secretion and tear film rupture time in the intervention group was better than that in the control group， the difference was statistically significant（P<0.05）. Conclusion The treatment of sodium hyaluronate eye drops and clinical interventions is more effective in operation derived dry eye patients， which can effectively reduce the dry eye symptoms and enhance the tear film stability of patients. It is worthy of clinical application.

[Key words] Operation derived dry eye; Sodium hyaluronate eye drops; Clinical interventions; Dry eye symptoms

干眼是眼科中较常见的一种病症，手术源性干眼是其中较为特殊的一种类型[1]。近些年来，随着临床对干眼病症研究的不断深入，越来越多的报道发现，部分眼科患者术后会出现疼痛、畏光、干涩、异物感等症状，检查显示泪膜破裂时间缩短，泪液分泌量改变，此种现象称之为手术源性干眼，具有很强的隐蔽性，容易受到忽视，出现误诊[2]。为此，对于手术源性干眼患者来说，必须给予及时、有效的临床干预，从而有效改善患者症状，加快患者康复。本文现选取2018年1月～2020年1月在我院治疗的106例手术源性干眼患者为观察对象，探讨临床干预措施的应用效果，现报道如下。

1 资料与方法

1.1 一般资料

选取2018年1月～2020年1月在我院治疗的106例手术源性干眼患者为观察对象，按照随机原则分成对照组与干预组，每组53例。……