何小霞　袁炜华　冯月平

【摘要】 目的 比较生化检验和常规尿液检验在糖尿病诊断中的应用效果。方法 150例疑似糖尿病患者， 分别进行常规尿液检查和生化检查， 比较各单项及联合检验的敏感度、特异度、阳性预测值、阴性预测值。结果 150例疑似糖尿病患者确诊108例， 占72.0%。常规尿液检验、生化检验以及尿检联合生化检验诊断糖尿病的敏感度分别为63.0%、87.0%、91.7%， 特异度分别为81.0%、85.7%、83.3%， 阳性预测值分别为89.5%、94.0%、93.4%， 阴性预测值分别为45.9%、72.0%、79.5%， 联合检验和生化检验的敏感度、阴性预测值明显高于尿液检验， 差异均具有统计学意义（P<0.05）;三种检验方法特异度和阳性预测值比较差异无统计学意义（P>0.05）。结论 生化检验在诊断糖尿病方面的敏感性和阴性预测优于常规尿液检验， 可大力推广应用。

【关键词】 糖尿病;诊断;常规尿液检验;生化检验;差异分析

DOI：10.14163/j.cnki.11-5547/r.2020.18.012

Analysis of the difference between routine urine test and biochemical test in the diagnosis of diabetes mellitus   HE Xiao-xia， YUAN Wei-hua， FENG Yue-ping. Yunfu Peoples Hospital， Yunfu 527300， China

【Abstract】 Objective   To compare the effect of between routine urine test and biochemical test on the diagnosis of diabetes mellitus. Methods   150 patients with suspected diabetes mellitus all received routine urine test and biochemical test respectively. The sensitivity， specificity， positive predictive value and negative predictive value of each single and combined test were compared. Results   Of the 150 suspected diabetic patients， 108 cases

were diagnosed， accounting for 72.0%. The sensitivity of routine urine test， biochemical test and urine test combined with biochemical test to diagnose diabetes mellitus were 63.0%， 87.0% and 91.7%， and the specificity was 81.0%， 85.7% and 83.3%， respectively， the positive predictive values were 89.5%， 94.0% and 93.4%， and the negative predictive values were 45.9%， 72.0% and 79.5%， respectively. The sensitivity and negative predictive value of combined test and biochemical test were higher than that of urine test， and the difference was statistically significant （P<0.05）. There was no statistically significant difference in specificity and positive predictive value among the three test methods （P>0.05）. Conclusion   The sensitivity and negative predictive value of biochemical test in diagnosing diabetes mellitis are better than routine urine test， and can be widely promoted and applied.

【Key words】 Diabetes mellitus; Diagnosis; Routine urine test; Biochemical test ; Difference analysis

糖尿病作为泌尿科的常见疾病， 近些年来随着生活环境和饮食习惯的改变， 其发病率呈显著上升趋势， 严重影响患者的健康[1]。糖尿病的预防及早期诊断对于患者预后具有重要意义， 其中常规尿液检验和生化检验是最常用的诊断方法[2]。本院为了验证生化检验和常规尿液检验在糖尿病中的诊断价值， 以部分患者作为对象进行对照研究， 现将结果汇报如下。

1 资料与方法

1. 1 一般资料 选取2019年1～12月本院收治的150例

疑似糖尿病患者作為研究对象， 其中男80例， 女70例;年龄38～69岁， 平均年龄（54.8±5.6）岁。排除合并严重的心血管疾病、肿瘤类疾病、血液类疾病以及精神障碍等患者， 确保不会对研究结果产生影响。

1. 2 方法 对纳入的150例疑似糖……