吗啡经皮下持续泵入在晚期癌痛患者镇痛中的效果观察及不良反应发生率影响评价
2019-10-21彭玉玲
彭玉玲


【摘 要】目的:分析吗啡经皮下持续泵入在晚期癌痛患者镇痛中的效果观察及不良反应发生率影响。方法:将2017年1月至2019年7月本院收治的48例晚期癌痛患者为研究对象,随机分为试验组与常规组各24例。临床镇痛中常规组使用硫酸吗啡缓释片治疗,试验组吗啡经皮下持续泵入镇痛,比较两组患者的镇痛效果及不良反应发生率。结果:治疗后患者的疼痛感受均得到缓解。试验组患者治疗期间出现2例不良反应低于常规组的8例,(p<0.05)。结论:吗啡经皮下持续泵入治疗晚期癌痛的效果较好,患者疼痛感受得到明显控制,且不良反应发生率较低,适合于临床推广。
【关键词】吗啡经皮下持续泵入;晚期癌痛患者;镇痛;不良反应
【中图分类号】R473.73【文献识别码】B【文章编号】1002-8714(2019)11-0032-02
【abstract】 objective: to analyze the effect of continuous subcutaneous pumping of morphine on analgesia and the incidence of adverse reactions in patients with advanced cancer pain.Methods: a total of 48 patients with advanced cancer pain admitted to our hospital from January 2017 to July 2019 were randomly divided into the experimental group and the conventional group with 24 cases each.In clinical analgesia, morphine sulfate sustained release tablets were used in the conventional group and morphine was continuously pumped into analgesia subcutaneously in the experimental group. The analgesic effect and adverse reaction incidence of the two groups were compared.Results: the pain was relieved after treatment.During treatment, 2 cases of adverse reactions occurred in the experimental group compared with 8 cases in the conventional group (p < 0.05).Conclusion: morphine is effective in the treatment of advanced cancer pain by subcutaneous continuous pumping. The pain perception of patients is obviously controlled and the incidence of adverse reactions is low.
【key words】 morphine was continuously pumped subcutaneously;Patients with advanced cancer pain;Analgesia;Adverse reactions
癌痛为晚期恶性肿瘤患者常见的症状,患者的痛苦感受强烈,需要使用药物缓解其疼痛感受[1]。吗啡为临床常用的镇痛药物,持续泵入治疗的方式下,符合晚期癌痛患者口服药物困难的特征,能够更好的发挥镇痛效果。文章将2017年1月至2019年7月在本院实施诊治的48例晚期癌痛患者视为研究对象,根据分组比较的结果,评估吗啡经皮下持续泵入的效果,且将内容归纳如下。
1 资料与方法
1.1 一般资料
将2017年1月至2019年7月在本院实施诊治的48例晚期癌痛患者视为研究对象,随机分为试验组与常规组(n=24)。常规组病患中男女占比为13:11,年龄范围38-71岁。肺癌8例,肝癌7例,乳腺癌5例,胰腺癌4例。试验组病患中男女占比为12:12,年龄范围37-71岁。肺癌8例,肝癌7例,乳腺癌5例,胰腺癌4例。两组间数据比较无显著差距,可以纳入两组对照研究(p>0.05)。
1.2 入选标准
(1)患者均通过病理学检……
