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尿激酶与低分子肝素钙联用治疗急性心肌梗死的效果和安全性评价

2019-08-19朱瑞国

中外医疗 2019年15期
关键词:低分子肝素钙尿激酶急性心肌梗死

朱瑞国

[摘要] 目的 分析在急性心肌梗死的治疗中应用尿激酶与低分子肝素钙联用治疗的临床效果。 方法 方便选取2017年3月—2019年1月进入该院接受治疗的急性心肌梗死患者共68例,将其随机分组,实验组34例患者接受尿激酶与低分子肝素钙联用治疗,对照组34例患者接受常规治疗。结果 临床治疗效率方面,实验组临床治疗效率为91.18%,对照组临床治疗效率为73.53%(χ2=4.376 1,P=0.036 4),实验组与对照组临床治疗效率差异有统计学意义(P<0.05)。血管再通情况方面,治疗后,实验组血管再通情况显著优于对照组(P<0.05)。在并发症控制情况方面,实验组并发症发生几率为5.88%;对照组并发症发生几率为29.41%(χ2=6.476 2,P=0.010 9),实验组并发症发生几率与对照组相比显著较低,差异有统计学意义(P<0.05)。结论  与常规保乳术治疗相比,在早期乳腺癌治疗中应用整形保乳术治疗的效果更显著,可以明显降低患者并发症发生几率,故方案推广意义大。

[关键词] 尿激酶;低分子肝素钙;急性心肌梗死;并发症率

[中图分类号] R5          [文献标识码] A          [文章编号] 1674-0742(2019)05(c)-0141-03

[Abstract] Objective To analyze the clinical effect of urokinase combined with low molecular weight heparin calcium in the treatment of acute myocardial infarction. Methods Convenient select a total of 68 patients with acute myocardial infarction who underwent treatment in our hospital from March 2017 to January 2019 were randomly divided into two groups. 34 patients in the experimental group received urokinase combined with low molecular weight heparin calcium. Patients received routine treatment in the control group. Results In terms of clinical treatment efficiency, the clinical treatment efficiency of the experimental group was 91.18%, the clinical treatment efficiency of the control group was 73.53% (χ2=4.376 1, P<0.036 4). The clinical treatment efficiency of the experimental group and the control group was significantly different (P<0.05). In terms of recanalization, after treatment, the recanalization of the experimental group was significantly better than that of the control group(P<0.05). In terms of complication control, the incidence of complications in the experimental group was 5.88%; the incidence of complications in the control group was 29.41%(χ2=6.476 2, P=0.010 9). The incidence of complications in the experimental group was significantly higher than that in the control group(P<0.05). Conclusion Compared with conventional breast conserving surgery, the application of plastic breast conserving therapy in the treatment of early breast cancer is more effective, which can significantly reduce the incidence of complications in patients, so the promotion of the program is of great significance.

[Key words] Urokinase; Low molecular weight heparin calcium; Acute myocardial infarction; Complication rat

急性心肌梗死是指患者动脉持续性、长时间的血液供应不足,进而導致的氧气供应不足,最终患者的心肌出现部分坏死,部分急性心肌梗死患者在病发前往往合并一些基础疾病,基础疾病在外界的刺激下,形成急性心肌出血,还有部分患者是由于心肌耗氧量骤增引起的急性心肌梗死。临床研究表明[1],过度劳累、情绪起伏波动大、饮食不合理、外界刺激以及年龄都是急性心肌梗死的诱发因素,随着国内经济的迅速发展,人口老龄化趋势的加快,急性心肌梗死的患者人数呈现逐年上升的趋势。该组实验方便选取2017年3月—2019年1月进入该院接受治疗的急性心肌梗死患者共68例作为研究样本,分别给予不同治疗方案。现将具体报道如下。

综上所述,与常规治疗相比,在急性心肌梗死的治疗中应用尿激酶与低分子肝素钙联用治疗的效果更显著,可以明显提升患者临床治疗效率,改善患者血管再通情况,降低患者并发症发生几率,故方案推广意义大。

[参考文献]

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(收稿日期:2019-02-23)

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